Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL772374 | 0.84 | KMT2A (0.69) | MAPK1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL7584842 | 0.83 | MAPK1 (0.60) | MAPK1KMT2ARAB9AALDH1A1 | |
| SCHEMBL8935936 | 0.82 | MAPK1 (1.00) | MAPK1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL29811681 | 0.82 | MAPK1 (1.00) | MAPK1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL2875215 | 0.82 | KMT2A (0.59) | MAPK1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL22242662 | 0.82 | KMT2A (0.59) | MAPK1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL2875218 | 0.82 | KMT2A (0.59) | MAPK1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL8939993 | 0.81 | ALDH1A1 (0.64) | MAPK1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL14951096 | 0.81 | MAPK1 (0.64) | MAPK1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL31605916 | 0.79 | MAPK1 (0.58) | MAPK1KMT2ARAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170319696-A1 | Derivatized Hyperbranched Polyglycerols | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2017-11-09 | — | — | US | disclosed |
| US-9561278-B2 | Derivatized hyperbranched polyglycerols | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2017-02-07 | — | — | US | disclosed |
| US-20160114040-A1 | Derivatized Hyperbranched Polyglycerols | CENTRE FOR DRUG RESEARCH AND DEVELOPMENT (CA) | 2016-04-28 | — | — | US | disclosed |
| US-9186410-B2 | Derivatized hyperbranched polyglycerols | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2015-11-17 | — | — | US | disclosed |
| US-20130122112-A1 | Derivatized Hyperbranched Polyglycerols | CENTRE FOR DRUG RESEARCH AND DEVELOPMENT (CA) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160114040-A1 | Derivatized Hyperbranched Polyglycerols | DDOST, UGCG, DAD1 | MAPK1 4709/4885KMT2A 3642/4885RAB9A 2656/4885 |
| US-20130122112-A1 | Derivatized Hyperbranched Polyglycerols | DDOST, UGCG, DAD1 | MAPK1 4709/4885KMT2A 3642/4885RAB9A 2656/4885 |
| US-20170319696-A1 | Derivatized Hyperbranched Polyglycerols | DDOST, UGCG, DAD1 | MAPK1 4709/4885KMT2A 3642/4885RAB9A 2656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.