Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.85 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.85 |
| ▸ | GALR3 | O60755 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.61 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | SLCO2A1 | Q92959 | 2/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25608056 | 0.92 | MAPT (1.00) | MAPTUCHL3GALR3ALDH1A1TRPA1 | |
| SCHEMBL13649348 | 0.92 | MAPT (1.00) | MAPTUCHL3GALR3ALDH1A1TRPA1 | |
| SCHEMBL5700581 | 0.92 | MAPT (1.00) | MAPTUCHL3GALR3ALDH1A1TRPA1 | |
| SCHEMBL8350588 | 0.92 | MAPT (1.00) | MAPTUCHL3GALR3ALDH1A1TRPA1 | |
| SCHEMBL13905975 | 0.92 | MAPT (1.00) | MAPTUCHL3GALR3ALDH1A1TRPA1 | |
| SCHEMBL8350586 | 0.92 | MAPT (1.00) | MAPTUCHL3GALR3ALDH1A1TRPA1 | |
| SCHEMBL5700584 | 0.92 | MAPT (1.00) | MAPTUCHL3GALR3ALDH1A1TRPA1 | |
| SCHEMBL10865862 | 0.92 | MAPT (0.85) | MAPTUCHL3GALR3ALDH1A1TRPA1 | |
| SCHEMBL22607967 | 0.92 | MAPT (1.00) | MAPTUCHL3GALR3ALDH1A1TRPA1 | |
| SCHEMBL11119548 | 0.92 | MAPT (0.85) | MAPTUCHL3GALR3ALDH1A1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9783592-B2 | Glucagon superfamily peptides exhibiting nuclear hormone receptor activity | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2017-10-10 | — | — | US | disclosed |
| US-20150320871-A1 | Glucagon Superfamily Peptides Exhibiting Nuclear Hormone Receptor Activity | UNIV INDIANA RES & TECH CORP (US) | 2015-11-12 | — | — | US | disclosed |
| US-9127088-B2 | Glucagon superfamily peptides exhibiting nuclear hormone receptor activity | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2015-09-08 | — | — | US | disclosed |
| US-20130123178-A1 | GLUCAGON SUPERFAMILY PEPTIDES EXHIBITING NUCLEAR HORMONE RECEPTOR ACTIVITY | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150320871-A1 | Glucagon Superfamily Peptides Exhibiting Nuclear Hormone Receptor Activity | GIPR, GLP1R, GCGR | MAPT 4294/4885UCHL3 2090/4885GALR3 101/4885 |
| US-20130123178-A1 | GLUCAGON SUPERFAMILY PEPTIDES EXHIBITING NUCLEAR HORMONE RECEPTOR ACTIVITY | GIPR, GLP1R, GCGR | MAPT 4294/4885UCHL3 2090/4885GALR3 101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.