Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | UCHL3 | P15374 | 1/20 | 1.00 |
| ▸ | GALR3 | O60755 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.73 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.73 |
| ▸ | HPGD | P15428 | 2/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.73 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.73 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.73 |
| ▸ | SLCO2A1 | Q92959 | 2/20 | 0.62 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.62 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.56 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.56 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.56 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13649348 | 1.00 | MAPT (1.00) | MAPTUCHL3GALR3ALDH1A1TRPA1 | |
| SCHEMBL8350588 | 1.00 | MAPT (1.00) | MAPTUCHL3GALR3ALDH1A1TRPA1 | |
| SCHEMBL22607967 | 1.00 | MAPT (1.00) | MAPTUCHL3GALR3ALDH1A1TRPA1 | |
| SCHEMBL13905975 | 1.00 | MAPT (1.00) | MAPTUCHL3GALR3ALDH1A1TRPA1 | |
| SCHEMBL5700581 | 1.00 | MAPT (1.00) | MAPTUCHL3GALR3ALDH1A1TRPA1 | |
| SCHEMBL25608056 | 1.00 | MAPT (1.00) | MAPTUCHL3GALR3ALDH1A1TRPA1 | |
| SCHEMBL8350586 | 1.00 | MAPT (1.00) | MAPTUCHL3GALR3ALDH1A1TRPA1 | |
| SCHEMBL14948544 | 0.92 | MAPT (0.85) | MAPTUCHL3GALR3ALDH1A1TRPA1 | |
| SCHEMBL10865862 | 0.92 | MAPT (0.85) | MAPTUCHL3GALR3ALDH1A1TRPA1 | |
| SCHEMBL11119548 | 0.92 | MAPT (0.85) | MAPTUCHL3GALR3ALDH1A1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954844-A | (5Z,13E,15S)-15-Hydroxy-11-oxoprosta-5,9.13-trien-1-oic acid and esters | G. D. SEARLE & CO. (US) | 1976-05-04 | — | — | US | claimed |
| EP-1310256-B1 | Use of prostaglandin A or its derivatives for the treatment of psoriasis | SYNPHORA AB (SE) | 2006-06-21 | — | — | EP | disclosed |
| EP-1310256-A2 | Use of prostaglandin A or its derivatives for the treatment of psoriasis | Synphora AB (SE) | 2003-05-14 | — | — | EP | disclosed |
| EP-0778774-B1 | NEW USE OF PROSTAGLANDINS | SYNPHORA AB (SE) | 2003-04-09 | — | — | EP | disclosed |
| EP-0782447-B1 | USE OF PROSTAGLANDINS FOR THE MANUFACTURE OF A MEDICAMENT FOR PREVENTION AND TREATMENT OF SECONDARY CATARACT | SYNPHORA AB (SE) | 2002-02-27 | — | — | EP | disclosed |
| US-6031001-A | Use of prostaglandins | SYNPHRA AB (SE) | 2000-02-29 | — | — | US | disclosed |
| US-5760075-A | Method and means for prevention and treatment of secondary cataract | PHARMACIA & UPJOHN AB (SE) | 1998-06-02 | — | — | US | disclosed |
| US-3954844-A | (5Z,13E,15S)-15-Hydroxy-11-oxoprosta-5,9.13-trien-1-oic acid and esters | G. D. SEARLE & CO. (US) | 1976-05-04 | — | — | US | disclosed |
| US-3954844-A | (5Z,13E,15S)-15-Hydroxy-11-oxoprosta-5,9.13-trien-1-oic acid and esters | G. D. SEARLE & CO. (US) | 1976-05-04 | — | — | US | disclosed |