Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.54 |
| ▸ | RELA | Q04206 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13467572 | 0.83 | GAA (0.82) | GAAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL17081335 | 0.83 | GAA (0.60) | GAAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5188523 | 0.82 | SMN1; SMN2 (0.68) | GAAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11330877 | 0.81 | NPC1 (0.56) | GAAALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL2608534 | 0.80 | KMT2A (0.61) | GAAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL15120767 | 0.79 | TSHR (0.47) | GAAALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL3742208 | 0.79 | SMN1; SMN2 (0.63) | GAAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3134087 | 0.79 | GAA (0.80) | GAAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL28577763 | 0.79 | GAA (0.79) | GAAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10973980 | 0.78 | POLB (0.81) | GAAALDH1A1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595995-B1 | HERBICIDAL ISOXAZOLO[5,4-B]PYRIDINES | BASF SE (DE) | 2015-11-25 | — | — | EP | disclosed |
| US-20130123105-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123105-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | CYP4X1, PNPO, PRDX4 | GAA 2044/4885ALDH1A1 292/4885KMT2A 2661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.