SCHEMBL14949124

SCHEMBL14949124

Cc1ccc(F)c(Cc2cc3ccccc3s2)c1

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 10/20 0.53
SLC5A1 P13866 6/20 0.53
CHRM1 P11229 1/20 0.53
ADRA1A P35348 1/20 0.53
SLC6A3 Q01959 1/20 0.53
CYP2A6 P11509 3/20 0.50
ADRB2 P07550 1/20 0.50
IDH1 O75874 1/20 0.47
ASIC3 Q9UHC3 1/20 0.46
LOXL2 Q9Y4K0 1/20 0.46
AGXT P21549 1/20 0.43
ADRA1D P25100 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17189237 0.83 SLC5A2 (0.51) SLC5A2SLC5A1CHRM1ADRA1ASLC6A3
SCHEMBL14278454 0.82 SLC5A2 (0.53) SLC5A2SLC5A1CYP2A6ADRB2IDH1
SCHEMBL28954986 0.82 CYP2A6 (0.50) SLC5A2SLC5A1CHRM1ADRA1ASLC6A3
SCHEMBL28528398 0.82 SLC5A2 (0.53) SLC5A2SLC5A1CHRM1ADRA1ASLC6A3
SCHEMBL155503 0.82 SLC5A2 (0.53) SLC5A2SLC5A1CHRM1ADRA1ASLC6A3
SCHEMBL19188793 0.82 SLC5A2 (0.53) SLC5A2SLC5A1CHRM1ADRA1ASLC6A3
SCHEMBL15681536 0.82 SLC5A2 (0.50) SLC5A2SLC5A1CHRM1ADRA1ASLC6A3
SCHEMBL18197565 0.80 SLC5A2 (0.48) SLC5A2SLC5A1CHRM1ADRA1ASLC6A3
SCHEMBL28201450 0.79 CYP2A6 (0.50) SLC5A2SLC5A1CHRM1ADRA1ASLC6A3
SCHEMBL16018613 0.79 CYP2A6 (0.47) SLC5A2SLC5A1CHRM1ADRA1ASLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4249462-A1 METHOD FOR PRODUCING KETONE DERIVATIVE Tokuyama Corporation (JP) 2023-09-27 EP disclosed
WO-2020129899-A1 METHOD FOR PRODUCING C-ARYL HYDROXY GLYCOXIDE DERIVATIVES 株式会社トクヤマ 2020-06-25 WO disclosed
WO-2020129901-A1 METHOD FOR PREPARING KETONE COMPOUND 株式会社トクヤマ 2020-06-25 WO disclosed
EP-3246324-A2 PHENYL C-GLUCOSIDE DERIVATIVE CONTAINING DEOXYGLUCOSE STRUCTURE, PREPARATION METHOD AND USES THEREOF Tianjin Institute Of Pharmaceutical Research (CN) 2017-11-22 EP disclosed
EP-2776449-B1 PROCESS FOR THE PREPARATION OF BETA-C-ARYL GLUCOSIDES SCINOPHARM TAIWAN LTD (TW) 2017-08-02 EP disclosed
US-20170057989-A1 PHENYL C-GLUCOSIDE DERIVATIVE CONTAINING DEOXYGLUCOSE STRUCTURE, PREPARATION METHOD AND USE THEREOF TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH (CN) 2017-03-02 US disclosed
US-9505734-B2 Phenyl C-glucoside derivative containing deoxyglucose structure, preparation method and use thereof TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH (CN) 2016-11-29 US disclosed
WO-2016098016-A1 PROCESS FOR THE PREPARATION OF SGLT2 INHIBITORS DR. REDDY’S LABORATORIES LIMITED (IN) 2016-06-23 WO disclosed
EP-2933250-A1 PHENYL C-GLUCOSIDE DERIVATIVE CONTAINING DEOXYGLUCOSE STRUCTURE, PREPARATION METHOD AND USE THEREOF Tianjin Institute Of Pharmaceutical Research (CN) 2015-10-21 EP disclosed
US-8952139-B2 Process for the preparation of β-C-aryl glucosides SCINOPHARM TAIWAN, LTD (TW) 2015-02-10 US disclosed
US-20140128595-A1 Process for the Preparation of ß-C-Aryl Glucosides SCINOPHARM TAIWAN, LTD. (TW) 2014-05-08 US disclosed
WO-2013068850-A2 PROCESS FOR THE PREPARATION OF β-C-ARYL GLUCOSIDES SCINOPHARM TAIWAN, LTD. (NA) 2013-05-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140128595-A1 Process for the Preparation of ß-C-Aryl Glucosides SLC5A2, SLC5A1, UGGT1 SLC5A2 1/4885SLC5A1 2/4885CHRM1 4790/4885
US-20170057989-A1 PHENYL C-GLUCOSIDE DERIVATIVE CONTAINING DEOXYGLUCOSE STRUCTURE, PREPARATION METHOD AND USE THEREOF GCG, SLC5A1, DPP7 SLC5A2 6/4885SLC5A1 2/4885CHRM1 1290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.