Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 12/20 | 0.83 |
| ▸ | CHRNA4 | P43681 | 12/20 | 0.83 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.65 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.65 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14949866 | 1.00 | CHRNB2 (0.83) | CHRNB2CHRNA4CHRNA3CHRNB3CHRNA6 | |
| SCHEMBL13307144 | 0.91 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA3CHRNB3CHRNA6 | |
| SCHEMBL15115391 | 0.91 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA3CHRNB3CHRNA6 | |
| SCHEMBL13308223 | 0.91 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA3CHRNB3CHRNA6 | |
| SCHEMBL3362182 | 0.91 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA3CHRNB3CHRNA6 | |
| SCHEMBL13307972 | 0.91 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA3CHRNB3CHRNA6 | |
| SCHEMBL7926666 | 0.91 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA3CHRNB3CHRNA6 | |
| SCHEMBL15106764 | 0.91 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA3CHRNB3CHRNA6 | |
| SCHEMBL7927113 | 0.91 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA3CHRNB3CHRNA6 | |
| SCHEMBL7927117 | 0.91 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA3CHRNB3CHRNA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445684-B2 | Nicotinic acetylcholine receptor ligands and the uses thereof | PsycoGenics Inc. (US) | 2013-05-21 | — | — | US | disclosed |