Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18909902 | 0.86 | PDK2 (0.39) | KMT2AMEN1SMN1; SMN2SCN9APOLB | |
| SCHEMBL361472 | 0.86 | SCN9A (0.37) | KMT2AMEN1SMN1; SMN2SCN9APOLB | |
| SCHEMBL30229597 | 0.85 | ALK (0.40) | KMT2AMEN1SMN1; SMN2SCN9APOLB | |
| SCHEMBL18344266 | 0.85 | ALK (0.40) | KMT2AMEN1SMN1; SMN2SCN9APOLB | |
| SCHEMBL18533588 | 0.84 | SCN9A (0.36) | KMT2AMEN1SMN1; SMN2SCN9APOLB | |
| SCHEMBL17612725 | 0.84 | SCN9A (0.36) | KMT2AMEN1SMN1; SMN2SCN9APOLB | |
| SCHEMBL365754 | 0.82 | HPGD (0.39) | KMT2AMEN1SMN1; SMN2SCN9APOLB | |
| SCHEMBL18533590 | 0.82 | PDK2 (0.36) | KMT2AMEN1SMN1; SMN2SCN9APOLB | |
| SCHEMBL17612729 | 0.82 | PDK2 (0.36) | KMT2AMEN1SMN1; SMN2SCN9APOLB | |
| SCHEMBL10033207 | 0.82 | BRD4 (0.36) | KMT2AMEN1SMN1; SMN2SCN9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593485-B1 | POLYMERS CRAFTET WITH AZOTIC MOLECULES | MICHELIN & CIE (FR) | 2016-03-23 | — | — | EP | disclosed |
| US-20130197237-A1 | MOLECULES HAVING COMBINABLE GROUPS | ARKEMA FRANCE (FR) | 2013-08-01 | — | — | US | disclosed |
| US-20130131279-A1 | GRAFT POLYMER TO WHICH COMBINED NITROGEN MOLECULES ARE GRAFTED | Mchelin Recherche et Technique S.A. (CH) | 2013-05-23 | — | — | US | disclosed |
| US-20130123418-A1 | RUBBER COMPOSITION CONTAINING A MODIFED ELASTOMER, METHOD FOR PREPARING SAME, AND TIRE CONTAINING SAME | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130197237-A1 | MOLECULES HAVING COMBINABLE GROUPS | NCAPH, NCL, PARG | KMT2A 3304/4885MEN1 1074/4885SMN1; SMN2 4018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.