Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10310217 | 1.00 | POLB (0.56) | POLBKDM4EHIF1AALDH1A1HSD17B10 | |
| SCHEMBL31084365 | 0.84 | POLB (0.42) | POLBKDM4EHIF1AALDH1A1HSD17B10 | |
| SCHEMBL10917165 | 0.83 | POLB (0.41) | POLBKDM4EHIF1AALDH1A1HSD17B10 | |
| SCHEMBL10914238 | 0.83 | POLB (0.41) | POLBKDM4EHIF1AALDH1A1LMNA | |
| SCHEMBL10916420 | 0.83 | CYP1A1 (0.48) | POLBKDM4EHIF1AALDH1A1HSD17B10 | |
| SCHEMBL10917276 | 0.83 | KDM4E (0.43) | POLBKDM4EHIF1AALDH1A1HSD17B10 | |
| SCHEMBL10921650 | 0.82 | POLB (0.44) | POLBKDM4EHIF1AALDH1A1HSD17B10 | |
| SCHEMBL13989109 | 0.82 | ALDH1A1 (0.41) | POLBKDM4EHIF1AALDH1A1HSD17B10 | |
| SCHEMBL21284339 | 0.82 | POLB (0.41) | POLBKDM4EHIF1AALDH1A1HSD17B10 | |
| SCHEMBL10916999 | 0.82 | ALDH1A1 (0.56) | POLBKDM4EALDH1A1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068874-A1 | ANTIBODY-DRUG CONJUGATES | PFIZER INC. (US) | 2013-05-16 | — | — | WO | disclosed |