Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | ACACA | Q13085 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5032099 | 0.89 | MAPT (0.47) | KMT2AMEN1MAPTRXFP1PPARG | |
| SCHEMBL14945613 | 0.85 | KMT2A (0.55) | KMT2AMEN1MAPTRXFP1PPARG | |
| SCHEMBL14945512 | 0.85 | KMT2A (0.43) | KMT2AMEN1MAPTRXFP1PPARG | |
| SCHEMBL23479896 | 0.83 | POLB (0.48) | KMT2AMEN1MAPTRXFP1PPARG | |
| SCHEMBL18097001 | 0.83 | MAPT (0.43) | KMT2AMEN1MAPTRXFP1PPARG | |
| SCHEMBL5132782 | 0.83 | MAPT (0.43) | KMT2AMEN1MAPTRXFP1PPARG | |
| SCHEMBL5133464 | 0.82 | MAPT (0.48) | KMT2AMEN1MAPTRXFP1PPARG | |
| SCHEMBL14945486 | 0.82 | MAPT (0.44) | KMT2AMEN1MAPTRXFP1PPARG | |
| SCHEMBL14948696 | 0.80 | ADORA2B (0.43) | KMT2AMEN1MAPTRXFP1PPARG | |
| SCHEMBL18096859 | 0.79 | MAPT (0.45) | KMT2AMEN1MAPTRXFP1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013071169-A1 | ACC INHIBITORS AND USES THEREOF | Nimbus Apollo, Inc. (US) | 2013-05-16 | — | — | WO | disclosed |