⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14950744 | 1.00 | — | — | |
| SCHEMBL14950649 | 1.00 | — | — | |
| SCHEMBL29712064 | 0.84 | — | — | |
| Ammonia Solution, Strong SCHEMBL10952009 | 0.81 | APLNR (0.32) | — | |
| SCHEMBL17591493 | 0.75 | — | — | |
| SCHEMBL20343929 | 0.73 | — | — | |
| SCHEMBL15541327 | 0.69 | — | — | |
| SCHEMBL11016285 | 0.69 | — | — | |
| SCHEMBL729382 | 0.67 | GAA (0.39) | — | |
| SCHEMBL12037362 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3020712-A1 | METHOD FOR PREPARING CYCLOPROPANE DERIVATIVES | Aratana Therapeutics NV (BE) | 2016-05-18 | — | — | EP | disclosed |
| EP-2776414-B1 | METHOD FOR PREPARING CYCLOPROPANE DERIVATIVES | ARATANA THERAPEUTICS NV (BE) | 2016-03-16 | — | — | EP | disclosed |
| US-9040699-B2 | Method for preparing cyclopropane derivatives | ARATANA THERAPEUTICS NV (BE) | 2015-05-26 | — | — | US | disclosed |
| US-9040699-B2 | Method for preparing cyclopropane derivatives | ARATANA THERAPEUTICS NV (BE) | 2015-05-26 | — | — | US | disclosed |
| US-20150051394-A1 | METHOD FOR PREPARING CYCLOPROPANE DERIVATIVES | ARATANA THERAPEUTICS NV (BE) | 2015-02-19 | — | — | US | disclosed |
| US-20150051394-A1 | METHOD FOR PREPARING CYCLOPROPANE DERIVATIVES | ARATANA THERAPEUTICS NV (BE) | 2015-02-19 | — | — | US | disclosed |
| WO-2013068042-A1 | METHOD FOR PREPARING CYCLOPROPANE DERIVATIVES | OKAPI SCIENCES NV (BE) | 2013-05-16 | — | — | WO | disclosed |