Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10055040 | 0.91 | FFAR1 (0.68) | PPARAFFAR1 | |
| SCHEMBL15458722 | 0.88 | HIF1A (0.67) | PPARAFFAR1 | |
| SCHEMBL2185809 | 0.86 | FFAR1 (0.70) | PPARAFFAR1 | |
| SCHEMBL2188996 | 0.84 | PPARA (0.79) | PPARAFFAR1 | |
| SCHEMBL2309613 | 0.83 | PPARA (0.86) | PPARAFFAR1 | |
| SCHEMBL14758954 | 0.83 | FFAR1 (0.70) | PPARAFFAR1 | |
| SCHEMBL12581587 | 0.83 | MRGPRX4 (0.73) | PPARAFFAR1 | |
| SCHEMBL21370449 | 0.82 | PPARA (0.83) | PPARAFFAR1 | |
| SCHEMBL15761768 | 0.81 | CA1 (0.62) | PPARA | |
| SCHEMBL259701 | 0.81 | MAPT (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013070660-A1 | TRICYCLIC AMINO CONTAINING COMPOUNDS FOR TREATMENT OR PREVENTION OF SYMPTOMS ASSOCIATED WITH ENDOCRINE DYSFUNCTION | EMORY UNIVERSITY (US) | 2013-05-16 | — | — | WO | disclosed |