Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21241028 | 0.90 | MAPT (0.64) | MAPTNPC1RAB9ARECQLHTT | |
| SCHEMBL11831264 | 0.89 | HTT (0.63) | MAPTNPC1RAB9ARECQLHTT | |
| SCHEMBL11660536 | 0.86 | MAPT (0.52) | MAPTNPC1RAB9ARECQLHTT | |
| SCHEMBL6690772 | 0.86 | HTT (0.57) | HTTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL20723944 | 0.85 | MAPT (0.58) | MAPTNPC1RAB9ARECQLHTT | |
| SCHEMBL6074740 | 0.84 | HTT (0.68) | MAPTNPC1RAB9ARECQLHTT | |
| Hydrochloric Acid SCHEMBL27300450 | 0.82 | HTT (0.66) | MAPTNPC1RAB9ARECQLHTT | |
| Bromide SCHEMBL27480159 | 0.82 | HTT (0.66) | MAPTNPC1RAB9ARECQLHTT | |
| SCHEMBL13920564 | 0.82 | MAPT (0.55) | MAPTNPC1RAB9ARECQLHTT | |
| SCHEMBL4951737 | 0.82 | MAPT (0.59) | MAPTNPC1RAB9ARECQLHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117123281-B | Long-acting catalyst of carbon-coated Fe-Ni alloy, and preparation method and application thereof | 宁夏大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-117123281-A | Long-acting catalyst of carbon-coated Fe-Ni alloy, and preparation method and application thereof | 宁夏大学 | 2023-11-28 | — | — | CN | disclosed |
| CN-116253648-A | Synthesis method of aromatic amine compound without metal participation | 西安交通大学 | 2023-06-13 | — | — | CN | disclosed |
| CN-111848412-B | Method for efficiently realizing N-alkylation reaction by using cycloiridium catalyst | 赣南医学院 | 2023-05-12 | — | — | CN | disclosed |
| CN-107922428-B | Thienopyrrole compounds and their use as inhibitors of oplophorus-derived luciferase | 普洛麦格公司 | 2021-02-05 | — | — | CN | disclosed |
| CN-111848412-A | Method for efficiently realizing N-alkylation reaction by using cycloiridium catalyst | 赣南医学院 | 2020-10-30 | — | — | CN | disclosed |
| US-20200063110-A1 | THIENOPYRROLE COMPOUNDS AND USES THEREOF | PROMEGA CORPORATION | 2020-02-27 | — | — | US | disclosed |
| EP-3313846-A1 | THIENOPYRROLE COMPOUNDS AND USES THEREOF AS INHIBITORS OF OPLOPHORUS-DERIVED LUCIFERASES | Promega Corporation (US) | 2018-05-02 | — | — | EP | disclosed |
| CN-107922428-A | Thienopyrroles compound and its purposes as the inhibitor for piercing shrimp source property luciferase | 普洛麦格公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-107129442-A | A kind of α Process for the cyanation of monoalkyl substituted aniline | 重庆大学 | 2017-09-05 | — | — | CN | disclosed |
| WO-2002085838-A1 | COPPER-CATALYZED FORMATION OF CARBON-HETEROATOM AND CARBON-CARBON BONDS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2002-10-31 | — | — | WO | disclosed |
| US-4801750-A | Process for the produciton of 2-chloroacetoacetic acid amides | LONZA LTD. (CH) | 1989-01-31 | — | — | US | disclosed |
| EP-0132920-A1 | Monoazo dye | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-02-13 | — | — | EP | disclosed |
| US-4443615-A | ANILINE, GLYCOL OR EPOXIDE, SILICA AND/OR ALUMINA CATALYST | TANABE SEIYAKU CO., LTD. (JP) | 1984-04-17 | — | — | US | disclosed |
| US-4319913-A | Substituted benzazaphospholes, herbicidal compositions and the use thereof | MONSANTO COMPANY (US) | 1982-03-16 | — | — | US | disclosed |
| US-4196287-A | Process for the catalytic production of 2-substituted pyridines | LONZA LTD. (CH) | 1980-04-01 | — | — | US | disclosed |
| US-4180513-A | ALKYLATION, OXIDATION, LEUCO DYES, TRIARYLMETHANE DYES | POLAROID CORPORATION (US) | 1979-12-25 | — | — | US | disclosed |
| US-4172944-A | Water insoluble styryl dyestuffs having hetero-aryl methylene substituent | BAYER AKTIENGESELLSCHAFT (DE) | 1979-10-30 | — | — | US | disclosed |
| US-4046771-A | GREENISH-YELLOW SHADES ON SYNTHETIC FIBERS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-06 | — | — | US | disclosed |
| US-4016191-A | WATER INSOLUBLE; LIGHTFASTNESS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200063110-A1 | THIENOPYRROLE COMPOUNDS AND USES THEREOF | THOP1, TYMP, CREBBP | MAPT 2973/4885NPC1 4190/4885RAB9A 3584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.