Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAPDH | P04406 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7202835 | 0.78 | EPHX2 (0.49) | ALDH1A1MEN1KMT2A | |
| SCHEMBL9736138 | 0.77 | CYP2C19 (0.55) | CYP2C19HDAC1HDAC11HDAC8HDAC6 | |
| SCHEMBL7202278 | 0.73 | EPHX2 (0.46) | — | |
| SCHEMBL17009256 | 0.72 | CYP2C19 (0.49) | CYP2C19RAB9AALDH1A1TSHRLMNA | |
| SCHEMBL10708130 | 0.72 | CTNNB1 (0.43) | HDAC1HDAC8KMT2ATDP1L3MBTL1 | |
| Dodecane SCHEMBL27753469 | 0.71 | TAAR1 (0.45) | CYP2C19HDAC1HDAC11HDAC8HDAC6 | |
| Decane SCHEMBL27733094 | 0.71 | TAAR1 (0.45) | CYP2C19HDAC1HDAC11HDAC8HDAC6 | |
| SCHEMBL7202275 | 0.71 | CNR1 (0.47) | KMT2A | |
| SCHEMBL27990231 | 0.70 | CYP2C19 (0.45) | CYP2C19HDAC1HDAC11HDAC8HDAC6 | |
| SCHEMBL8942994 | 0.70 | CYP2C19 (0.45) | CYP2C19HDAC1HDAC11HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2034011-B1 | CELL CLUSTER COMPRISING PLURAL KINDS OF CELLS DERIVED FROM SOMA WITH ABILITY TO FORM PRIMITIVE ORGAN-LIKE STRUCTURE | SHISEIDO CO LTD (JP) | 2013-05-22 | — | — | EP | claimed |