SCHEMBL9736138

SCHEMBL9736138

CCCCCCCC(Cc1cccs1)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.55
GRIK1 P39086 2/20 0.44
GRIK2 Q13002 2/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC11 Q96DB2 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
RAB9A P51151 1/20 0.43
CTSC P53634 1/20 0.42
SLC1A2 P43004 1/20 0.42
SLC1A1 P43005 1/20 0.42
FNTA P49354 2/20 0.41
FNTB P49356 2/20 0.41
PGGT1B P53609 2/20 0.41
TSHR P16473 2/20 0.41
GLA P06280 1/20 0.41
HTT P42858 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CA2 P00918 1/20 0.41
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2400082 0.82 CYP2C19 (0.66) CYP2C19RAB9ACTSCSLC1A2SLC1A1
SCHEMBL17762784 0.82 CYP2C19 (0.66) CYP2C19RAB9ACTSCSLC1A2SLC1A1
SCHEMBL17009256 0.81 CYP2C19 (0.49) CYP2C19RAB9ACTSCFNTAFNTB
SCHEMBL7350157 0.81 CYP2C19 (0.75) CYP2C19RAB9ACTSCSLC1A2SLC1A1
SCHEMBL27990231 0.79 CYP2C19 (0.45) CYP2C19HDAC1HDAC11HDAC8HDAC6
SCHEMBL8942994 0.79 CYP2C19 (0.45) CYP2C19HDAC1HDAC11HDAC8HDAC6
SCHEMBL23844741 0.79 L3MBTL1 (0.43) CYP2C19HDAC1HDAC11HDAC8HDAC6
SCHEMBL16863665 0.79 L3MBTL1 (0.43) CYP2C19HDAC1HDAC11HDAC8HDAC6
SCHEMBL2710505 0.79 L3MBTL1 (0.43) CYP2C19HDAC1HDAC11HDAC8HDAC6
SCHEMBL19526473 0.79 L3MBTL1 (0.43) CYP2C19HDAC1HDAC11HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5098599-A Aromatic esters with sulfide groups as liquid crystals MITSUBISHI RAYON COMPANY LTD. (JP) 1992-03-24 US disclosed