SCHEMBL14957451

SCHEMBL14957451

O=CCCCCCN1C(=O)C=CC1=O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 10/20 0.71
FAAH O00519 5/20 0.71
ALDH1A1 P00352 2/20 0.71
LMNA P02545 2/20 0.71
MAPT P10636 2/20 0.71
NPSR1 Q6W5P4 2/20 0.71
HSP90AA1 P07900 1/20 0.71
TLR9 Q9NR96 1/20 0.71
TP53 P04637 1/20 0.71
PKM P14618 1/20 0.71
HPGD P15428 1/20 0.71
XBP1 P17861 1/20 0.71
MAPK1 P28482 1/20 0.71
HTT P42858 1/20 0.71
RECQL P46063 1/20 0.71
RAB9A P51151 1/20 0.71
SMN1; SMN2 Q16637 1/20 0.71
GPR35 Q9HC97 1/20 0.71
GPR55 Q9Y2T6 1/20 0.71
PTGS1 P23219 7/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19514775 1.00 MGLL (0.71) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL19514804 0.98 MGLL (0.70) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL7516512 0.91 MGLL (0.65) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL20351983 0.84 MGLL (1.00) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL258626 0.84 MGLL (1.00) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL818349 0.84 MGLL (1.00) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL5383694 0.84 MGLL (1.00) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL13815841 0.84 MGLL (1.00) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL549065 0.84 MGLL (1.00) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL141227 0.84 MGLL (1.00) MGLLFAAHALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116419929-B Engineered EGFR antibodies with reduced affinity, drug conjugates and uses thereof 百力司康生物医药(杭州)有限公司 2024-03-08 CN claimed
CN-107921144-B Aureostatin analogs and conjugate conjugates thereof with cell-binding molecules 杭州多禧生物科技有限公司 2023-11-28 CN claimed
CN-116726190-A Aureostatin analogs and conjugate conjugates thereof with cell-binding molecules 杭州多禧生物科技有限公司 2023-09-12 CN claimed
CN-116547304-A Engineering antibodies, antibody conjugated drugs and uses thereof 百力司康生物医药(杭州)有限公司 2023-08-04 CN claimed
CN-116528911-A anti-CD 73 antibody, antibody-conjugated drug and application thereof 百力司康生物医药(杭州)有限公司 2023-08-01 CN claimed
CN-116419929-A Engineered EGFR antibodies with reduced affinity, drug conjugates and uses thereof 百力司康生物医药(杭州)有限公司 2023-07-11 CN claimed
CN-116406382-A anti-CD 276 antibody, antibody-conjugated drug and application thereof 百力司康生物医药(杭州)有限公司 2023-07-07 CN claimed
CN-116143678-A Conjugate linker, cell-binding molecule-drug conjugate containing the same, and preparation and application thereof 杭州多禧生物科技有限公司 2023-05-23 CN claimed
CN-111848792-B Preparation method and detection method of antibody of bovine serum albumin and other impurities in vaccine 浙江省食品药品检验研究院 2023-02-24 CN claimed
CN-114901699-A Epitopes of anti-Serine Protease Inhibitor KAZAL (SPIK) antibodies 英凯尔生物科技有限责任公司 2022-08-12 CN claimed
CN-114262344-A Charged linkers and their use in conjugation reactions 杭州多禧生物科技有限公司 2022-04-01 CN claimed
CN-114174341-A anti-Serine Protease Inhibitor KAZAL (SPIK) antibodies, immunoconjugates and methods of use 英凯尔生物科技有限责任公司 2022-03-11 CN claimed
CN-110643032-B Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2022-01-28 CN claimed
CN-111848792-A Preparation method and detection method of antibody of bovine serum albumin and other impurities in vaccine 浙江省食品药品检验研究院 2020-10-30 CN claimed
CN-110643032-A Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2020-01-03 CN claimed
CN-104147612-A Tumor microenvironment specific activated micromolecular targeted conjugate and application thereof YAFEI SHANGHAI BIO PHARMACEUTICAL CO LTD 2014-11-19 CN claimed
CN-120923996-B Modified polyester film for automobile windows and preparation method thereof 圣乐帝(江西)薄膜科技有限公司 2026-04-07 CN disclosed
US-12514928-B2 Herboxidiene antibody-drug conjugates and methods of use EISAI R&D MANAGEMENT CO., LTD. (JP) 2026-01-06 US disclosed
CN-102596260-A Zirconium-radiolabeled, cysteine engineered antibody conjugates HOFFMANN LA ROCHE 2012-07-18 CN disclosed
CN-101267842-A Use of conjugates of doxorubicin with lactosaminated albumin UNI DI BOLOGNA DIPARTIMENTO DI (IT) 2008-09-17 CN disclosed