Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70233 | 0.87 | KDM4E (0.62) | KDM4EALDH1A1HSD17B10MAPTGAA | |
| SCHEMBL27442731 | 0.87 | GAA (0.50) | KDM4EALDH1A1HSD17B10MAPTGAA | |
| SCHEMBL30870705 | 0.87 | GAA (0.50) | KDM4EALDH1A1HSD17B10MAPTGAA | |
| SCHEMBL2427491 | 0.86 | KDM4E (0.57) | KDM4EALDH1A1HSD17B10MAPTGAA | |
| SCHEMBL3121267 | 0.84 | HSD17B10 (0.52) | KDM4EALDH1A1HSD17B10MAPTGAA | |
| SCHEMBL1483525 | 0.84 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10MAPTGAA | |
| SCHEMBL16950448 | 0.84 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10MAPTGAA | |
| SCHEMBL29606243 | 0.84 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10MAPTGAA | |
| SCHEMBL1483367 | 0.83 | MAPT (0.59) | KDM4EALDH1A1HSD17B10MAPTGAA | |
| SCHEMBL5089887 | 0.83 | KDM4E (0.49) | KDM4EALDH1A1HSD17B10MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2782449-B1 | ISOXAZOLINE DERIVATIVES USED IN THE CONTROL OF ECTOPARASITES | ANACOR PHARMACEUTICALS INC (US) | 2016-08-03 | — | — | EP | disclosed |
| CN-104066330-B | Isoxazoline derivatives for controlling ectoparasites | ANACOR PHARMACEUTICALS, INC. (US) | 2016-05-18 | — | — | CN | disclosed |
| EP-2782449-A1 | ISOXAZOLINE DERIVATIVES USED IN THE CONTROL OF ECTOPARASITES | Anacor Pharmaceuticals, Inc. (US) | 2014-10-01 | — | — | EP | disclosed |
| US-8546357-B2 | Boron-containing small molecules for controlling ectoparasites | ELI LILLY AND COMPANY (US) | 2013-10-01 | — | — | US | disclosed |
| WO-2013078071-A1 | ISOXAZOLINE DERIVATIVES USED IN THE CONTROL OF ECTOPARASITES | ELI LILLY AND COMPANY (US) | 2013-05-30 | — | — | WO | disclosed |
| US-20130131017-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2013-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131017-A1 | BORON-CONTAINING SMALL MOLECULES | BCL6B, BCL6, RB1 | KDM4E 2393/4885ALDH1A1 4298/4885HSD17B10 2443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.