Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.62 |
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | ATM | Q13315 | 3/20 | 0.62 |
| ▸ | GLA | P06280 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | CASP1 | P29466 | 1/20 | 0.62 |
| ▸ | CASP7 | P55210 | 1/20 | 0.62 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | CA7 | P43166 | 3/20 | 0.53 |
| ▸ | CA9 | Q16790 | 3/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.53 |
| ▸ | XDH | P47989 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3121267 | 0.89 | HSD17B10 (0.52) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL29606243 | 0.89 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL16950448 | 0.89 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL1483525 | 0.89 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL17888585 | 0.89 | NOTUM (0.57) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL28058610 | 0.89 | NOTUM (0.57) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL5089887 | 0.87 | KDM4E (0.49) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL14958355 | 0.87 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL2427491 | 0.87 | KDM4E (0.57) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL16869883 | 0.86 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4651988-A1 | METHODS OF MAKING METAL-ORGANIC FRAMEWORKS WITH PRE-LIGANDS | ExxonMobil Technology and Engineering Company (US) | 2025-11-26 | — | — | EP | claimed |
| US-20240300983-A1 | Method of Making Metal-Organic Frameworks With a Precursor and Crystallization Aid | EXXONMOBIL TECHNOLOGY & ENGINEERING COMPANY (US) | 2024-09-12 | — | — | US | claimed |
| US-20240254148-A1 | METHODS OF MAKING METAL-ORGANIC FRAMEWORKS WITH PRE-LIGANDS | EXXONMOBIL TECHNOLOGY & ENGINEERING COMPANY (US) | 2024-08-01 | — | — | US | claimed |
| WO-2024155562-A1 | METHODS OF MAKING METAL-ORGANIC FRAMEWORKS WITH PRE-LIGANDS | ExxonMobil Technology and Engineering Company (US) | 2024-07-25 | — | — | WO | claimed |
| EP-4363100-A1 | METHOD OF MAKING METAL-ORGANIC FRAMEWORKS WITH A PRECURSOR AND CRYSTALLIZATION AID | ExxonMobil Technology and Engineering Company (US) | 2024-05-08 | — | — | EP | claimed |
| WO-2023278248-A1 | METHOD OF MAKING METAL-ORGANIC FRAMEWORKS WITH A PRECURSOR AND CRYSTALLIZATION AID | ExxonMobil Technology and Engineering Company (US) | 2023-01-05 | — | — | WO | claimed |
| CN-112592361-B | Fluoroboropyrrole functionalized metal organic framework material and preparation method and application thereof | 江苏大学 | 2022-05-20 | — | — | CN | claimed |
| CN-112592361-A | Fluoroboropyrrole functionalized metal organic framework material and preparation method and application thereof | 江苏大学 | 2021-04-02 | — | — | CN | claimed |
| CN-106432898-B | A kind of high barrier composite membrane | 苍南县宝丰印业有限公司 | 2019-01-15 | — | — | CN | claimed |
| JP-11279123-A | — | — | None | — | — | JP | disclosed |
| EP-4081521-B1 | SUBSTITUTED TRICYCLIC COMPOUNDS | LUPIN LTD (IN) | 2025-12-10 | — | — | EP | disclosed |
| EP-4651988-A1 | METHODS OF MAKING METAL-ORGANIC FRAMEWORKS WITH PRE-LIGANDS | ExxonMobil Technology and Engineering Company (US) | 2025-11-26 | — | — | EP | disclosed |
| US-20250346585-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2025-11-13 | — | — | US | disclosed |
| US-20240300983-A1 | Method of Making Metal-Organic Frameworks With a Precursor and Crystallization Aid | EXXONMOBIL TECHNOLOGY & ENGINEERING COMPANY (US) | 2024-09-12 | — | — | US | disclosed |
| CN-1092776-A | 2-(9-Fluorenone base) carbapeneme intermediate | MERCK & CO INC (US) | 1994-09-28 | — | — | CN | disclosed |
| US-5144028-A | Antibiotics | MERCK & CO., INC. (US) | 1992-09-01 | — | — | US | disclosed |
| EP-0472306-A1 | 2-(9-fluorenonyl)-carbapenem antibacterial agents | MERCK & CO. INC. (US) | 1992-02-26 | — | — | EP | disclosed |
| EP-0469844-A1 | 2-(9-fluorenonyl)-carbapenem | MERCK & CO. INC. (US) | 1992-02-05 | — | — | EP | disclosed |
| US-5034384-A | Bactericides, antibiotics for resistant bacteria | MERCK & CO., INC. (US) | 1991-07-23 | — | — | US | disclosed |
| US-5025007-A | 2-(9-fluorenonyl)-carbapenem antibacterial agents | MERCK & CO., INC. (US) | 1991-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250346585-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | C5, C1S, C9 | KDM4E 4647/4885ALDH1A1 1707/4885HSD17B10 2484/4885 |
| US-20240254148-A1 | METHODS OF MAKING METAL-ORGANIC FRAMEWORKS WITH PRE-LIGANDS | HCAR3, POF1B, HCAR1 | KDM4E 3465/4885ALDH1A1 363/4885HSD17B10 280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.