SCHEMBL14958604

SCHEMBL14958604

c1ccc(-c2cccc(-c3ccc4c5ccccc5c5ccccc5c4c3)c2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.48
ESR1 P03372 1/20 0.48
KMT2A Q03164 1/20 0.48
MAOA P21397 1/20 0.46
ALDH1A1 P00352 2/20 0.45
KMO O15229 1/20 0.45
ALOX5 P09917 1/20 0.44
ACMSD Q8TDX5 1/20 0.44
JAK2 O60674 2/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
HSD17B1 P14061 1/20 0.42
HSD17B2 P37059 1/20 0.42
PLA2G2A P14555 3/20 0.42
PLA2G4A P47712 3/20 0.42
PLA2G10 O15496 1/20 0.42
ABL1 P00519 1/20 0.41
ABCB1 P08183 1/20 0.41
BCR P11274 1/20 0.41
MGLL Q99685 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25668832 1.00 MEN1 (0.48) MEN1ESR1KMT2AMAOAALDH1A1
SCHEMBL20431790 1.00 MEN1 (0.48) MEN1ESR1KMT2AMAOAALDH1A1
SCHEMBL22173462 1.00 MEN1 (0.48) MEN1ESR1KMT2AMAOAALDH1A1
SCHEMBL19878962 1.00 MEN1 (0.48) MEN1ESR1KMT2AMAOAALDH1A1
SCHEMBL25669185 1.00 MEN1 (0.48) MEN1ESR1KMT2AMAOAALDH1A1
SCHEMBL23432303 1.00 MEN1 (0.48) MEN1ESR1KMT2AMAOAALDH1A1
SCHEMBL24712638 0.98 MEN1 (0.46) MEN1ESR1KMT2AMAOAALDH1A1
SCHEMBL20431772 0.95 ALDH1A1 (0.45) MEN1ESR1KMT2AMAOAALDH1A1
SCHEMBL311659 0.95 ESR1 (0.46) MEN1ESR1KMT2AMAOAKMO
SCHEMBL311937 0.95 ESR1 (0.46) MEN1ESR1KMT2AMAOAKMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8445120-B2 Triphenylene based aromatic compounds and OLEDs utilizing the same NATIONAL TSING HUA UNIVERSITY (TW) 2013-05-21 US disclosed