SCHEMBL14958720

SCHEMBL14958720

CCCCCCn1ncc(N)c1C

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 2/20 0.39
SLC9A1 P19634 2/20 0.38
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15652073 0.93 POLB (0.40) SLC9A1POLB
SCHEMBL15651754 0.85 POLB (0.50) SLC9A1POLB
SCHEMBL11969241 0.84 TLR8 (0.40) TLR8SLC9A1
SCHEMBL11990846 0.84 TLR8 (0.40) TLR8SLC9A1
SCHEMBL6243840 0.84 TLR8 (0.40) TLR8SLC9A1
SCHEMBL18921050 0.84 TLR8 (0.40) TLR8SLC9A1
SCHEMBL2476916 0.81 TLR8 (0.41) TLR8SLC9A1
SCHEMBL31319659 0.81 TLR8 (0.38) TLR8SLC9A1
Hydrochloric Acid SCHEMBL5654701 0.80 TLR8 (0.42) TLR8SLC9A1
SCHEMBL14959689 0.78 TLR8 (0.36) TLR8SLC9A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8444711-B2 Oxidative dyeing compositions comprising an 1-hexyl/heptyl-4,5-diaminopyrazole and a benzene-1,3-diamine and derivatives thereof THE PROCTER & GAMBLE COMPANY (US) 2013-05-21 US disclosed
US-8444713-B2 Oxidative dyeing compositions comprising an 1-hexyl/heptyl-4,5-diaminopyrazole and a naphthalen-1-ol and derivatives thereof THE PROCTER & GAMBLE COMPANY (US) 2013-05-21 US disclosed
US-8444709-B2 Oxidative dyeing compositions comprising an 1-hexyl/heptyl-4,5-diaminopyrazole and a 2-aminophenol and derivatives thereof THE PROCTER & GAMBLE COMPANY (US) 2013-05-21 US disclosed
US-8444714-B2 Oxidative dyeing compositions comprising an 1-Hexy1/Hepty1-4,5-diaminopyrazole and a benzene-1,3-diol and derivatives thereof THE PROCTER & GAMBLE COMPANY (US) 2013-05-21 US disclosed