SCHEMBL2476916

SCHEMBL2476916

CCCCCn1ncc(N)c1N

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 3/20 0.41
SLC9A1 P19634 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18921050 0.98 TLR8 (0.40) TLR8SLC9A1
SCHEMBL11969241 0.98 TLR8 (0.40) TLR8SLC9A1
SCHEMBL6243840 0.98 TLR8 (0.40) TLR8SLC9A1
SCHEMBL11990846 0.98 TLR8 (0.40) TLR8SLC9A1
Hydrochloric Acid SCHEMBL5654701 0.98 TLR8 (0.42) TLR8SLC9A1
SCHEMBL5387962 0.94 SLC9A1 (0.36) TLR8SLC9A1
Sulfuric Acid SCHEMBL2922590 0.90 TP53 (0.39)
Sulfuric Acid SCHEMBL19689610 0.89 TP53 (0.38)
SCHEMBL5159269 0.86 POLB (0.40) SLC9A1
SCHEMBL3944376 0.86 TSHR (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 455 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12383482-B2 Hair coloring compositions WELLA GERMANY GMBH (DE) 2025-08-12 US claimed
EP-4251285-B1 HAIR COLORING COMPOSITIONS WELLA INT OPERATIONS SWITZERLAND SARL (CH) 2024-09-04 EP claimed
US-20240024218-A1 HAIR COLORING COMPOSITIONS WELLA GERMANY GMBH (DE) 2024-01-25 US claimed
CN-117396185-A Hair dyeing composition 威娜国际运营瑞士责任有限公司 2024-01-12 CN claimed
US-11142498-B2 Keratin dyeing compounds, compositions containing them, and method and use thereof WELLA OPERATIONS US, LLC (US) 2021-10-12 US claimed
US-20200247749-A1 KERATIN DYEING COMPOUNDS, COMPOSITIONS CONTAINING THEM, AND METHOD AND USE THEREOF WELLA OPERATIONS US, LLC 2020-08-06 US claimed
EP-3263180-B1 METHOD FOR COLORING HAIR FIBERS INTO A FIRST AND A SECOND PATTERNS NOXELL CORP (US) 2020-04-08 EP claimed
US-20190269945-A1 METHOD FOR COLORING HAIR FIBERS INTO A FIRST AND A SECOND PATTERNS NOXELL CORP (US) 2019-09-05 US claimed
EP-3281623-B1 HAIR COLORING COMPOSITION FOR PROVIDING A FILM ON KERATIN FIBERS NOXELL CORP (US) 2019-07-31 EP claimed
US-20190201308-A1 METHOD FOR COLORING HAIR NOXELL CORPORATION 2019-07-04 US claimed
WO-2005023209-A1 AGENT AND METHOD FOR DYEING KERATIN FIBERS WELLA AKTIENGESELLSCHAFT (DE) 2005-03-17 WO claimed
EP-1313434-B1 OXIDATION DYE WELLA AG (DE) 2005-01-12 EP claimed
US-6793687-B2 YELLOW AND ORANGE RANGE COLORING WELLA AKTIENGESELLSCHAFT (DE) 2004-09-21 US claimed
WO-2004047781-A1 N-ARYL-4,5-DIAMINOPYRAZOLS AND DYES CONTAINING SAID COMPOUNDS WELLA AKTIENGESELLSCHAFT (DE) 2004-06-10 WO claimed
US-20030159222-A1 Oxidation dye HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2003-08-28 US claimed
US-20030131423-A1 Diaminopyrazole derivatives and oxidation hair dye containing pyrazolone derivatives HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2003-07-17 US claimed
EP-1313434-A1 OXIDATION DYE Wella Aktiengesellschaft (DE) 2003-05-28 EP claimed
EP-1257249-A1 DIAMINOPYRAZOLE DERIVATIVES AND OXIDATION HAIR DYE CONTAINING PYRAZOLONE DERIVATIVES Wella Aktiengesellschaft (DE) 2002-11-20 EP claimed
WO-2002069919-A1 OXIDATION DYE WELLA AKTIENGESELLSCHAFT (DE) 2002-09-12 WO claimed
WO-2002069918-A1 DIAMINOPYRAZOLE DERIVATIVES AND OXIDATION HAIR DYE CONTAINING PYRAZOLONE DERIVATIVES WELLA AKTIENGESELLSCHAFT (DE) 2002-09-12 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190201308-A1 METHOD FOR COLORING HAIR TYR, CYB5R3, ALDH1A3 TLR8 3510/4885SLC9A1 1164/4885
US-20030159222-A1 Oxidation dye KRT18, NOX4, VIM TLR8 2236/4885SLC9A1 409/4885
US-11142498-B2 Keratin dyeing compounds, compositions containing them, and method and use thereof KRT18, MARK4, MKI67 TLR8 4351/4885SLC9A1 3207/4885
US-20190269945-A1 METHOD FOR COLORING HAIR FIBERS INTO A FIRST AND A SECOND PATTERNS COXFA4L2, KRT18, SHH TLR8 4527/4885SLC9A1 3785/4885
US-20200247749-A1 KERATIN DYEING COMPOUNDS, COMPOSITIONS CONTAINING THEM, AND METHOD AND USE THEREOF KRT18, PRKDC, MKI67 TLR8 4307/4885SLC9A1 3273/4885
US-20030131423-A1 Diaminopyrazole derivatives and oxidation hair dye containing pyrazolone derivatives KRT18, AOC1, PPOX TLR8 3867/4885SLC9A1 500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.