Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 3/20 | 0.32 |
| ▸ | CCR1 | P32246 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.31 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3440437 | 0.82 | CHRM5 (0.54) | CHRM5ADRA2CACHESMN1; SMN2ALDH1A1 | |
| SCHEMBL26416120 | 0.75 | BRD4 (0.31) | POLB | |
| SCHEMBL22941470 | 0.74 | GBA1 (0.39) | CHRM5ADRA2CACHESMN1; SMN2CCR1 | |
| SCHEMBL24003427 | 0.72 | SMN1; SMN2 (0.40) | SMN1; SMN2CCR1 | |
| SCHEMBL23023325 | 0.72 | POLB (0.36) | POLBL3MBTL1L3MBTL3OPRM1OPRL1 | |
| SCHEMBL24196541 | 0.69 | CHRM5 (0.48) | CHRM5ADRA2CACHESMN1; SMN2KDM4E | |
| SCHEMBL14536447 | 0.69 | KDM4E (0.35) | CHRM5ADRA2CACHECCR2POLB | |
| SCHEMBL19723232 | 0.69 | KDM4E (0.35) | CHRM5ADRA2CACHECCR2POLB | |
| SCHEMBL16385349 | 0.69 | KDM4E (0.35) | CHRM5ADRA2CACHECCR2KDM4E | |
| SCHEMBL2621572 | 0.69 | POLB (0.36) | CHRM5ADRA2CACHECCR2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402329-B1 | Analgetic phenylsulphonamides | BOEHRINGER INGELHEIM INT (DE) | 2013-05-22 | — | — | EP | disclosed |