Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 14/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10118727 | 0.92 | BDKRB1 (0.59) | BDKRB1GFERKMT2A | |
| SCHEMBL3440537 | 0.91 | BDKRB1 (0.59) | BDKRB1 | |
| SCHEMBL3440208 | 0.90 | BDKRB1 (0.54) | BDKRB1KMT2A | |
| SCHEMBL12914508 | 0.85 | POLB (0.55) | BDKRB1GFERKMT2A | |
| SCHEMBL3440040 | 0.85 | BDKRB1 (0.53) | BDKRB1GFERKMT2A | |
| SCHEMBL3440534 | 0.84 | BDKRB1 (0.47) | BDKRB1GFERREV1KMT2A | |
| SCHEMBL3440009 | 0.84 | BDKRB1 (0.51) | BDKRB1GFER | |
| SCHEMBL3440280 | 0.84 | BDKRB1 (0.51) | BDKRB1GFER | |
| SCHEMBL14958754 | 0.84 | MAPT (0.54) | BDKRB1KMT2A | |
| SCHEMBL3444042 | 0.84 | BDKRB1 (0.57) | BDKRB1GFERREV1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402329-B1 | Analgetic phenylsulphonamides | BOEHRINGER INGELHEIM INT (DE) | 2013-05-22 | — | — | EP | disclosed |