SCHEMBL1495920

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1495972	0.89	KMT2A (0.47)	MAPTTP53KCNN4KCNA3ALDH1A1
	SCHEMBL13273471	0.87	KCNN4 (0.51)	MAPTKCNN4KCNA3CYP2C9KMT2A
	SCHEMBL6350658	0.85	MAPT (0.48)	MAPTTP53CYP2C9POLB
	SCHEMBL4868711	0.79	MAPT (0.43)	MAPTTP53CYP2C9ALDH1A1KMT2A
	SCHEMBL31058571	0.78	KCNN4 (0.51)	MAPTKCNN4KCNA3CYP2C9KMT2A
	SCHEMBL25562472	0.78	KCNN4 (0.51)	MAPTKCNN4KCNA3CYP2C9KMT2A
	SCHEMBL768700	0.76	KCNN4 (0.67)	MAPTTP53KCNN4KCNA3CYP2C9
	SCHEMBL17158242	0.72	KCNN4 (0.50)	MAPTTP53KCNN4KCNA3CYP2C9
	SCHEMBL2514016	0.72	KCNN4 (0.55)	MAPTKCNN4KCNA3CYP2C9KMT2A
	SCHEMBL12679669	0.72	KCNN4 (0.55)	MAPTKCNN4KCNA3CYP2C9KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.