Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GLP1R | P43220 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | NQO1 | P15559 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10348834 | 0.78 | MAPT (0.52) | MEN1NPC1USP2POLBMAPT | |
| Hydrochloric Acid SCHEMBL9797561 | 0.75 | MAPT (0.50) | MEN1NPC1USP2POLBMAPT | |
| SCHEMBL13058525 | 0.75 | MAPT (0.42) | MEN1NPC1MAPTKMT2AALDH1A1 | |
| SCHEMBL6108326 | 0.68 | TERT (0.56) | MEN1NPC1USP2POLBMAPT | |
| SCHEMBL29428970 | 0.67 | KMT2A (0.72) | MEN1NPC1USP2POLBMAPT | |
| SCHEMBL837057 | 0.67 | KMT2A (0.72) | MEN1NPC1USP2POLBMAPT | |
| SCHEMBL9832575 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL31429077 | 0.64 | KMT2A (0.68) | MEN1NPC1USP2POLBMAPT | |
| Hydrochloric Acid SCHEMBL31429084 | 0.64 | KMT2A (0.68) | MEN1NPC1USP2POLBMAPT | |
| SCHEMBL13156612 | 0.64 | KMT2A (0.68) | MEN1NPC1USP2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445678-B2 | 2-quinoxalinol salen compounds and uses thereof | AUBURN UNIVERSITY (US) | 2013-05-21 | — | — | US | disclosed |