Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | STIM1 | Q13586 | 5/20 | 0.41 |
| ▸ | ORAI1 | Q96D31 | 5/20 | 0.41 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 6/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 6/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1593863 | 0.93 | ALDH1A1 (0.63) | ALDH1A1MEN1HPGDKMT2AMAPT | |
| SCHEMBL1594122 | 0.78 | ALDH1A1 (0.67) | ALDH1A1MEN1HPGDKMT2AGAA | |
| SCHEMBL1594571 | 0.74 | ALDH1A1 (0.65) | ALDH1A1GAAL3MBTL1PTGES2HSD17B1 | |
| SCHEMBL1593805 | 0.74 | ALDH1A1 (0.61) | ALDH1A1GAAL3MBTL1PTGES2HSD17B1 | |
| SCHEMBL1593531 | 0.74 | ALDH1A1 (0.64) | ALDH1A1MEN1HPGDKMT2AMAPT | |
| SCHEMBL19400063 | 0.74 | ALDH1A1 (0.55) | ALDH1A1HPGDMAPTGAAL3MBTL1 | |
| SCHEMBL1595142 | 0.73 | ALDH1A1 (0.71) | ALDH1A1MEN1HPGDKMT2AMAPT | |
| SCHEMBL2058323 | 0.73 | ALDH1A1 (0.74) | ALDH1A1HPGDGAAL3MBTL1PTGES2 | |
| SCHEMBL1574357 | 0.73 | ALDH1A1 (0.74) | ALDH1A1HPGDMAPTGAAL3MBTL1 | |
| SCHEMBL1594595 | 0.72 | ALDH1A1 (0.65) | ALDH1A1MAPTGAAL3MBTL1PTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1989185-B1 | THERAPEUTIC COMPOUNDS | HELICON THERAPEUTICS INC (US) | 2013-05-22 | — | — | EP | disclosed |