Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2255925 | 0.84 | RAB9A (0.49) | RAB9APTGS1NPC1MAPTALDH1A1 | |
| SCHEMBL2252774 | 0.83 | RAB9A (0.50) | RAB9APTGS1NPC1MAPTALDH1A1 | |
| SCHEMBL2254610 | 0.80 | RAB9A (0.50) | RAB9APTGS1NPC1MAPTALDH1A1 | |
| SCHEMBL3658247 | 0.79 | NPY5R (0.48) | RAB9APTGS1NPC1MAPTALDH1A1 | |
| SCHEMBL3928750 | 0.78 | RAB9A (0.58) | RAB9APTGS1NPC1MAPTALDH1A1 | |
| SCHEMBL14960390 | 0.77 | NPY5R (0.47) | RAB9APTGS1NPC1NPY5RGAA | |
| SCHEMBL1465583 | 0.76 | RAB9A (0.57) | RAB9APTGS1NPC1MAPTALDH1A1 | |
| SCHEMBL16359181 | 0.75 | GAA (0.50) | RAB9APTGS1NPC1MAPTALDH1A1 | |
| SCHEMBL14960388 | 0.74 | GAA (0.49) | RAB9APTGS1NPC1TRPV1NPY5R | |
| SCHEMBL2256509 | 0.74 | NPY5R (0.53) | RAB9APTGS1NPC1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217565-B1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INT (DE) | 2013-05-22 | — | — | EP | disclosed |