SCHEMBL1496040

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19150871	0.76	ALDH1A1 (0.40)	ALDH1A1LMNAGAAHPGDHTT
	SCHEMBL10076399	0.74	ADORA1 (0.64)	ADORA1POLBMEN1ALDH1A1LMNA
	SCHEMBL17339841	0.73	CHEK1 (0.47)	ADORA1POLBALDH1A1LMNAGAA
	SCHEMBL12177816	0.72	ADORA1 (0.53)	BCHEADORA1POLBMEN1ALDH1A1
	SCHEMBL14432510	0.71	NPY5R (0.50)	ADORA1POLBPIK3CDPIK3CAPIK3CB
	SCHEMBL17905871	0.70	CDC7 (0.36)	ALDH1A1DAPK3CSNK1A1CLK4
	SCHEMBL12798139	0.69	CHEK1 (0.65)	ADORA1POLBMEN1TP53KMT2A
	SCHEMBL13545736	0.69	TYMS (0.39)	ACHEADORA1POLBALDH1A1HPGD
	SCHEMBL7342733	0.69	BCHE (0.43)	BCHEACHEBRD4POLBALDH1A1
	SCHEMBL2616315	0.69	ADORA1 (0.36)	ADORA1POLBPIK3CDPIK3CAPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.