Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.53 |
| ▸ | TP53 | P04637 | 4/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | OTUD7B | Q6GQQ9 | 2/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16253024 | 0.89 | RORC (0.59) | RORCRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL10802219 | 0.81 | RORC (0.63) | RORCRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL3772532 | 0.81 | RORC (0.66) | RORCRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL13901729 | 0.77 | MEN1 (0.82) | RORCRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL1464918 | 0.76 | CNR2 (0.59) | RORCRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL3775573 | 0.76 | RORC (0.47) | RORCRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL223464 | 0.75 | MAPT (0.62) | RORCRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL13962761 | 0.74 | MEN1 (0.72) | RORCRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL13901757 | 0.74 | SMN1; SMN2 (0.66) | RORCRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL13901730 | 0.74 | NPC1 (0.90) | RORCRAB9AMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217565-B1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INT (DE) | 2013-05-22 | — | — | EP | disclosed |