SCHEMBL14960903

SCHEMBL14960903

Cc1ccc(N(c2ccc(-c3ccc(/C=C(\C#N)OC=O)s3)cc2)c2ccc(-c3ccc(-c4ccc(/C=C(\C#N)C(=O)O)s4)s3)cc2)c(C)c1

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.58
APP P05067 3/20 0.50
KMT2A Q03164 5/20 0.37
MEN1 O00255 4/20 0.37
RAB9A P51151 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
LMNA P02545 1/20 0.37
POLB P06746 1/20 0.37
THRB P10828 1/20 0.37
SLC16A3 O15427 2/20 0.34
SLC16A1 P53985 2/20 0.34
ALDH1A1 P00352 2/20 0.32
NPC1 O15118 1/20 0.32
PSMD14 O00487 1/20 0.32
HPGD P15428 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14962655 0.91 MAPT (0.69) MAPTAPPKMT2AMEN1RAB9A
SCHEMBL11936927 0.88 MAPT (0.66) MAPTAPPKMT2AMEN1RAB9A
SCHEMBL11988574 0.85 MAPT (0.60) MAPTAPPKMT2AMEN1RAB9A
SCHEMBL17037812 0.85 MAPT (0.81) MAPTAPPKMT2AMEN1RAB9A
SCHEMBL14960890 0.83 MAPT (0.50) MAPTAPPKMT2AMEN1RAB9A
SCHEMBL3368159 0.81 MAPT (0.83) MAPTAPPKMT2AMEN1RAB9A
SCHEMBL11936959 0.81 MAPT (0.83) MAPTAPPKMT2AMEN1RAB9A
SCHEMBL11988591 0.81 MAPT (0.53) MAPTAPPKMT2AMEN1RAB9A
SCHEMBL11982883 0.81 MAPT (0.54) MAPTAPPKMT2AMEN1RAB9A
SCHEMBL11937018 0.80 MAPT (0.64) MAPTAPPKMT2AMEN1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130125987-A1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLAR BATTERY CONTAINING THE SAME KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2013-05-23 US disclosed