SCHEMBL3368159

SCHEMBL3368159

Cc1ccc(N(c2ccc(C)cc2)c2ccc(-c3ccc(-c4ccc(/C=C(\C#N)C(=O)O)s4)s3)cc2)cc1

nearest known ligand 0.83

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.83
APP P05067 3/20 0.69
KMT2A Q03164 5/20 0.42
MEN1 O00255 4/20 0.42
SLC16A3 O15427 1/20 0.42
SLC16A1 P53985 1/20 0.42
ALDH1A1 P00352 2/20 0.41
HPGD P15428 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
HSD17B1 P14061 1/20 0.41
HSD17B2 P37059 1/20 0.41
LMNA P02545 1/20 0.39
POLB P06746 1/20 0.39
THRB P10828 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PSMD14 O00487 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11936959 1.00 MAPT (0.83) MAPTAPPKMT2AMEN1SLC16A3
SCHEMBL14773202 0.98 MAPT (0.79) MAPTAPPKMT2AMEN1SLC16A3
SCHEMBL10058505 0.98 MAPT (0.79) MAPTAPPKMT2AMEN1SLC16A3
SCHEMBL7008387 0.97 MAPT (0.77) MAPTAPPKMT2AMEN1SLC16A3
SCHEMBL12673225 0.94 MAPT (0.93) MAPTAPPKMT2ASLC16A3SLC16A1
SCHEMBL11988635 0.92 MAPT (0.71) MAPTAPPKMT2AMEN1SLC16A3
SCHEMBL11941724 0.91 MAPT (0.70) MAPTAPPKMT2AMEN1ALDH1A1
SCHEMBL17040396 0.91 MAPT (1.00) MAPTAPPKMT2AMEN1SLC16A3
SCHEMBL12327641 0.91 MAPT (1.00) MAPTAPPKMT2AMEN1SLC16A3
SCHEMBL12294107 0.91 MAPT (1.00) MAPTAPPKMT2AMEN1SLC16A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1628356-B1 DYE-SENSITIZED PHOTOELECTRIC CONVERSION DEVICE NIPPON KAYAKU KK (JP) 2012-08-15 EP disclosed
US-8227690-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-07-24 US disclosed
US-8183393-B2 Dye compound and dye-sensitized solar cell ACADEMIA SINICA (TW) 2012-05-22 US disclosed
US-8183393-B2 Dye compound and dye-sensitized solar cell ACADEMIA SINICA (TW) 2012-05-22 US disclosed
US-8183393-B2 Dye compound and dye-sensitized solar cell ACADEMIA SINICA (TW) 2012-05-22 US disclosed
US-20100076205-A1 DYE COMPOUND AND DYE-SENSITIZED SOLAR CELL ACADEMIA SINICA (TW) 2010-03-25 US disclosed
US-20100076205-A1 DYE COMPOUND AND DYE-SENSITIZED SOLAR CELL ACADEMIA SINICA (TW) 2010-03-25 US disclosed
US-20100076205-A1 DYE COMPOUND AND DYE-SENSITIZED SOLAR CELL ACADEMIA SINICA (TW) 2010-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100076205-A1 DYE COMPOUND AND DYE-SENSITIZED SOLAR CELL CRY1, DSG1, CRY2 MAPT 4399/4885APP 2553/4885KMT2A 2034/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.