Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 20/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14964359 | 1.00 | IDO1 (0.39) | IDO1 | |
| SCHEMBL14964285 | 0.90 | ALDH1A1 (0.32) | IDO1 | |
| SCHEMBL14964283 | 0.90 | ALDH1A1 (0.32) | IDO1 | |
| SCHEMBL14964330 | 0.88 | IDO1 (0.40) | IDO1 | |
| SCHEMBL5631705 | 0.81 | IDO1 (0.41) | IDO1 | |
| SCHEMBL5631696 | 0.81 | IDO1 (0.41) | IDO1 | |
| SCHEMBL5631715 | 0.81 | IDO1 (0.41) | IDO1 | |
| SCHEMBL5631709 | 0.79 | IDO1 (0.58) | IDO1 | |
| SCHEMBL14964323 | 0.79 | IDO1 (0.32) | IDO1 | |
| SCHEMBL4972930 | 0.78 | IDO1 (0.31) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450351-B2 | N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase | INCYTE CORPORATION (US) | 2013-05-28 | — | — | US | claimed |