SCHEMBL14964618

SCHEMBL14964618

CCCCCCCCCCCCCCCCCC(=O)OC(C)(C)C.CCCCCCCCCCCCCCCCCC(=O)OC(C)(C)CN

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.46
LMNA P02545 3/20 0.43
PAM P19021 2/20 0.42
MAPT P10636 2/20 0.41
MAPK1 P28482 1/20 0.41
TSHR P16473 3/20 0.40
CES2 O00748 3/20 0.39
CES1 P23141 3/20 0.39
ALDH1A1 P00352 2/20 0.39
DNM1 Q05193 1/20 0.39
NAAA Q02083 1/20 0.39
PPARG P37231 3/20 0.38
PPARD Q03181 3/20 0.38
PPARA Q07869 3/20 0.38
GPR84 Q9NQS5 2/20 0.38
HDAC11 Q96DB2 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
SLC22A6 Q4U2R8 1/20 0.38
SLC22A8 Q8TCC7 1/20 0.38
TLR2 O60603 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7153688 0.95 DGKA (0.50) DGKALMNAPAMMAPTMAPK1
SCHEMBL14964640 0.95 DGKA (0.50) DGKALMNAPAMMAPTMAPK1
SCHEMBL8756165 0.95 DGKA (0.50) DGKALMNAPAMMAPTMAPK1
SCHEMBL3823631 0.88 DGKA (0.57) DGKALMNAPAMMAPTMAPK1
SCHEMBL5732818 0.88 DGKA (0.57) DGKALMNAPAMMAPTMAPK1
SCHEMBL3121472 0.88 DGKA (0.57) DGKALMNAPAMMAPTMAPK1
SCHEMBL7771101 0.88 DGKA (0.57) DGKALMNAPAMMAPTMAPK1
SCHEMBL62214 0.88 DGKA (0.57) DGKALMNAPAMMAPTMAPK1
SCHEMBL3662225 0.88 DGKA (0.57) DGKALMNAPAMMAPTMAPK1
SCHEMBL9985650 0.88 DGKA (0.57) DGKALMNAPAMMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2780302-A1 BLASTING COMPOSITIONS Dyno Nobel Asia Pacific Pty Limited (AU) 2014-09-24 EP disclosed
WO-2013071363-A1 BLASTING COMPOSITIONS DYNO NOBEL ASIA PACIFIC PTY LTD (AU) 2013-05-23 WO disclosed