Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16293085 | 0.84 | MEN1 (0.33) | — | |
| SCHEMBL14965351 | 0.83 | POLB (0.45) | — | |
| SCHEMBL14965494 | 0.81 | ADRB2 (0.30) | ADRB2ADRB1ADRB3 | |
| SCHEMBL14965130 | 0.77 | ELANE (0.31) | — | |
| SCHEMBL16293812 | 0.66 | POLB (0.50) | — | |
| SCHEMBL14965108 | 0.65 | POLB (0.47) | ADRB3 | |
| SCHEMBL16293556 | 0.64 | KMT2A (0.32) | ADRB2ADRB1ADRB3 | |
| SCHEMBL16293405 | 0.62 | — | — | |
| SCHEMBL14964960 | 0.62 | ADRB2 (0.35) | ADRB2ADRB1ADRB3 | |
| SCHEMBL14965302 | 0.62 | KMT2A (0.44) | ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780343-A1 | THIENO- AND FURO - PYRIMIDINES AND PYRIDINES, USEFUL AS POTASSIUM CHANNEL INHIBITORS | Xention Limited (GB) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013072694-A1 | THIENO- AND FURO - PYRIMIDINES AND PYRIDINES, USEFUL AS POTASSIUM CHANNEL INHIBITORS | XENTION LIMITED (GB) | 2013-05-23 | — | — | WO | disclosed |