Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14965131 | 0.91 | HTR1A (0.37) | HTR1AHTR1DHTR1B | |
| SCHEMBL14964891 | 0.82 | KDM4E (0.35) | — | |
| SCHEMBL14964951 | 0.77 | — | — | |
| SCHEMBL14964982 | 0.77 | HRH3 (0.40) | — | |
| SCHEMBL14965244 | 0.76 | HTR1A (0.38) | HTR1AHTR1DHTR1B | |
| SCHEMBL14965589 | 0.75 | — | — | |
| SCHEMBL27978487 | 0.75 | PTPN11 (0.33) | — | |
| SCHEMBL14965345 | 0.74 | HTR2A (0.36) | HTR1AHTR1DHTR1B | |
| SCHEMBL14965489 | 0.74 | KCNQ3 (0.34) | — | |
| SCHEMBL14964887 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780343-A1 | THIENO- AND FURO - PYRIMIDINES AND PYRIDINES, USEFUL AS POTASSIUM CHANNEL INHIBITORS | Xention Limited (GB) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013072694-A1 | THIENO- AND FURO - PYRIMIDINES AND PYRIDINES, USEFUL AS POTASSIUM CHANNEL INHIBITORS | XENTION LIMITED (GB) | 2013-05-23 | — | — | WO | disclosed |