Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Dimethylformamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylformamide SCHEMBL27977755 | 0.91 | — | — | |
| Dimethylformamide SCHEMBL5206086 | 0.91 | — | — | |
| Dimethylformamide SCHEMBL29091205 | 0.91 | TSHR (0.82) | — | |
| Dimethylformamide SCHEMBL28380960 | 0.91 | — | — | |
| Dimethylformamide SCHEMBL10423097 | 0.91 | — | — | |
| Dimethylformamide SCHEMBL11872125 | 0.91 | — | — | |
| Dimethylformamide SCHEMBL6013340 | 0.91 | — | — | |
| Dimethylformamide SCHEMBL3685915 | 0.91 | — | — | |
| Dimethylformamide SCHEMBL30504948 | 0.91 | — | — | |
| Dimethylformamide SCHEMBL27387268 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780348-B1 | PROCESS FOR THE PREPARATION OF TENOFOVIR | LAURUS LABS PRIVATE LTD (IN) | 2017-03-01 | — | — | EP | disclosed |
| CN-103917550-B | For the method preparing tenofovir | 劳拉斯实验室私人有限公司 | 2016-08-24 | — | — | CN | disclosed |
| US-9056882-B2 | Process for the preparation of tenofovir | LAURUS LABS PRIVATE LTD. (IN) | 2015-06-16 | — | — | US | disclosed |
| US-20140303368-A1 | PROCESS FOR THE PREPARATION OF TENOFOVIR | LAURUS LABS PRIVATE LIMITED (IN) | 2014-10-09 | — | — | US | disclosed |
| EP-2780348-A1 | PROCESS FOR THE PREPARATION OF TENOFOVIR | Laurus Labs Private Limited (IN) | 2014-09-24 | — | — | EP | disclosed |
| CN-103917550-A | Process for preparation of tenofovir | LAURUS LABS PRIVATE LTD | 2014-07-09 | — | — | CN | disclosed |
| WO-2013111148-A1 | PROCESS FOR PREPARATION OF LUTEOLIN | LAURUS LABS PRIVATE LIMITED (IN) | 2013-08-01 | — | — | WO | disclosed |
| WO-2013072745-A1 | PROCESS FOR THE PREPARATION OF TENOFOVIR | LAURUS LABS PRIVATE LIMITED (IN) | 2013-05-23 | — | — | WO | disclosed |