Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16292947 | 0.94 | ADRB3 (0.60) | LMNAADRB3 | |
| SCHEMBL16292822 | 0.91 | ADRB3 (0.60) | ADRB3 | |
| SCHEMBL17599009 | 0.87 | ADRB3 (0.58) | ADRB3 | |
| SCHEMBL24391624 | 0.87 | ADRB3 (0.59) | LMNAADRB3MEN1KMT2A | |
| SCHEMBL14964948 | 0.87 | ADRB3 (0.59) | LMNAADRB3KMT2A | |
| SCHEMBL4432115 | 0.85 | LMNA (0.72) | LMNAMEN1KMT2A | |
| SCHEMBL4552668 | 0.85 | LMNA (0.72) | LMNAMEN1KMT2A | |
| SCHEMBL16294397 | 0.85 | LMNA (0.72) | LMNAMEN1KMT2A | |
| SCHEMBL16293493 | 0.84 | ADRB3 (0.64) | ADRB3KMT2A | |
| SCHEMBL14965408 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780343-A1 | THIENO- AND FURO - PYRIMIDINES AND PYRIDINES, USEFUL AS POTASSIUM CHANNEL INHIBITORS | Xention Limited (GB) | 2014-09-24 | — | — | EP | disclosed |
| CN-104011054-A | Thieno- and furo-pyrimidines and pyridines, useful as potassium channel inhibitors | XENTION LTD | 2014-08-27 | — | — | CN | disclosed |
| WO-2013072694-A1 | THIENO- AND FURO - PYRIMIDINES AND PYRIDINES, USEFUL AS POTASSIUM CHANNEL INHIBITORS | XENTION LIMITED (GB) | 2013-05-23 | — | — | WO | disclosed |