Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.37 |
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14966043 | 0.81 | KMT2A (0.35) | GRIK1GRIK2SLC1A5FFAR1FFAR4 | |
| SCHEMBL5065706 | 0.76 | KMT2A (0.47) | GRIK1ALDH1A1CYP2C9TSHRCYP2C19 | |
| SCHEMBL19357525 | 0.73 | LMNA (0.45) | MAPT | |
| SCHEMBL19357526 | 0.73 | LMNA (0.45) | MAPT | |
| SCHEMBL4064873 | 0.73 | ALPI (0.43) | ALDH1A1CYP1A2CYP3A4TSHRHTT | |
| SCHEMBL18344466 | 0.73 | ALPI (0.43) | ALDH1A1CYP1A2CYP3A4TSHRHTT | |
| SCHEMBL5066181 | 0.73 | ALPI (0.43) | ALDH1A1CYP1A2CYP3A4TSHRHTT | |
| SCHEMBL10421321 | 0.72 | LMNA (0.42) | FFAR1HTR2AHTT | |
| SCHEMBL10421320 | 0.72 | LMNA (0.42) | FFAR1HTR2AHTT | |
| SCHEMBL16195856 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780448-B1 | BIOCATALYSTS FOR THE PREPARATION OF HYDROXY SUBSTITUTED CARBAMATES | CODEXIS INC (US) | 2019-09-11 | — | — | EP | claimed |
| EP-2780448-A1 | BIOCATALYSTS FOR THE PREPARATION OF HYDROXY SUBSTITUTED CARBAMATES | Codexis, Inc. (US) | 2014-09-24 | — | — | EP | claimed |
| WO-2013074650-A1 | BIOCATALYSTS FOR THE PREPARATION OF HYDROXY SUBSTITUTED CARBAMATES | CODEXIS, INC. (US) | 2013-05-23 | — | — | WO | claimed |
| EP-2780448-A1 | BIOCATALYSTS FOR THE PREPARATION OF HYDROXY SUBSTITUTED CARBAMATES | Codexis, Inc. (US) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013074650-A1 | BIOCATALYSTS FOR THE PREPARATION OF HYDROXY SUBSTITUTED CARBAMATES | CODEXIS, INC. (US) | 2013-05-23 | — | — | WO | disclosed |