SCHEMBL14966795

SCHEMBL14966795

CCC1(C)OC1C(=O)OC1CCCC1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.42
NAAA Q02083 2/20 0.40
CYP2C19 P33261 1/20 0.37
HTT P42858 2/20 0.35
FABP7 O15540 1/20 0.35
FABP5 Q01469 1/20 0.35
CHRM2 P08172 3/20 0.33
CHRM4 P08173 3/20 0.33
CHRM5 P08912 3/20 0.33
CHRM1 P11229 3/20 0.33
CHRM3 P20309 3/20 0.33
SMN1; SMN2 Q16637 1/20 0.31
CYP19A1 P11511 2/20 0.31
MAPK1 P28482 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967589 0.98 EPHX1 (0.45) EPHX1NAAACYP2C19HTTFABP7
SCHEMBL14967987 0.97 EPHX1 (0.39) EPHX1NAAACYP2C19HTTFABP7
SCHEMBL14968059 0.93 EPHX1 (0.33) EPHX1NAAA
SCHEMBL14967757 0.83 EPHX1 (0.42) EPHX1NAAACYP2C19HTTFABP7
SCHEMBL14966938 0.82 FABP7 (0.41) EPHX1NAAACYP2C19HTTFABP7
SCHEMBL14968044 0.81 EPHX1 (0.45) EPHX1NAAACYP2C19HTTFABP7
SCHEMBL14968354 0.80 FABP7 (0.44) EPHX1NAAACYP2C19HTTFABP7
SCHEMBL14967703 0.79 EPHX1 (0.39) EPHX1NAAACYP2C19HTTFABP7
SCHEMBL14966951 0.78 FABP7 (0.38) EPHX1NAAACYP2C19HTTFABP7
SCHEMBL9691853 0.76 PPM1B (0.32) SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed