SCHEMBL14967703

SCHEMBL14967703

CCC1(CC)OC1C(=O)OC1CCC1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.39
NAAA Q02083 2/20 0.37
CYP2C19 P33261 1/20 0.33
FABP7 O15540 1/20 0.32
FABP5 Q01469 1/20 0.32
HTT P42858 1/20 0.32
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31
PRSS1 P07477 1/20 0.30
TPSAB1 Q15661 1/20 0.30
TPSD1 Q9BZJ3 1/20 0.30
TPSG1 Q9NRR2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967757 0.97 EPHX1 (0.42) EPHX1NAAACYP2C19FABP7FABP5
SCHEMBL14968044 0.95 EPHX1 (0.45) EPHX1NAAACYP2C19FABP7FABP5
SCHEMBL14967573 0.93 EPHX1 (0.33) EPHX1NAAA
SCHEMBL14967987 0.83 EPHX1 (0.39) EPHX1NAAACYP2C19FABP7FABP5
SCHEMBL14966795 0.79 EPHX1 (0.42) EPHX1NAAACYP2C19FABP7FABP5
SCHEMBL14966951 0.78 FABP7 (0.38) EPHX1NAAACYP2C19FABP7FABP5
SCHEMBL14967589 0.78 EPHX1 (0.45) EPHX1NAAACYP2C19FABP7FABP5
SCHEMBL14968059 0.75 EPHX1 (0.33) EPHX1NAAA
SCHEMBL14966938 0.74 FABP7 (0.41) EPHX1NAAACYP2C19FABP7FABP5
SCHEMBL9692709 0.74 DNTT (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed