SCHEMBL14966796

SCHEMBL14966796

CC1(C(=O)Oc2ccccc2)OC1c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.43
POLB P06746 2/20 0.43
KMT2A Q03164 4/20 0.41
NPSR1 Q6W5P4 4/20 0.41
ALDH1A1 P00352 3/20 0.41
MAPT P10636 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
KDM4E B2RXH2 2/20 0.39
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ATM Q13315 2/20 0.37
ABCB1 P08183 1/20 0.36
GAA P10253 1/20 0.36
ELANE P08246 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16109082 0.91 USP2 (0.42) L3MBTL1POLBKMT2ANPSR1ALDH1A1
SCHEMBL14967580 0.90 EDNRA (0.43) L3MBTL1POLBALDH1A1MAPTGAA
SCHEMBL14968052 0.83 HTT (0.45) L3MBTL1POLBKMT2ANPSR1ALDH1A1
SCHEMBL14966775 0.81 L3MBTL1 (0.47) L3MBTL1POLBALDH1A1MAPTTDP1
SCHEMBL9511990 0.81 KMT2A (0.41) L3MBTL1POLBKMT2ANPSR1ALDH1A1
SCHEMBL14967898 0.80 MAPT (0.39) L3MBTL1POLBKMT2ANPSR1ALDH1A1
SCHEMBL14967706 0.79 TSHR (0.39) L3MBTL1POLBKMT2ANPSR1ALDH1A1
SCHEMBL57714 0.79 TSHR (0.49) KMT2ANPSR1ALDH1A1MAPTKDM4E
SCHEMBL14967416 0.79 L3MBTL1 (0.42) L3MBTL1POLBKMT2ANPSR1ALDH1A1
SCHEMBL5862723 0.79 KMT2A (0.40) L3MBTL1POLBKMT2ANPSR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed