Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21875403 | 0.81 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| Acetic Acid SCHEMBL29164016 | 0.80 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL29824155 | 0.79 | KDM4E (0.44) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL25360368 | 0.79 | KDM4E (0.44) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL2013864 | 0.77 | NPSR1 (0.47) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL30500676 | 0.76 | SOS1 (0.48) | KDM4EALDH1A1HPGDMAPTTSHR | |
| SCHEMBL25262355 | 0.76 | SOS1 (0.48) | KDM4EALDH1A1HPGDMAPTTSHR | |
| Trifluoroacetic Acid SCHEMBL25305646 | 0.76 | SOS1 (0.42) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL25360143 | 0.75 | GAA (0.41) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL27388974 | 0.74 | NPSR1 (0.44) | KDM4EALDH1A1HPGDGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072882-A1 | 2 -AMINO- 1, 8 -NAPHTHYRIDINE-3 -CARBOXAMIDE DERIVATIVES AS ANTIMICROBIAL AGENTS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-23 | — | — | WO | disclosed |