SCHEMBL14967338

SCHEMBL14967338

CCCCCCOC(=O)C1(c2ccc(OC)cc2)OC12CCCC2

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.44
CHRM1 P11229 1/20 0.44
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 3/20 0.42
SIGMAR1 Q99720 2/20 0.41
LMNA P02545 3/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
POLB P06746 1/20 0.39
TSHR P16473 2/20 0.38
MIF P14174 1/20 0.38
CNR1 P21554 2/20 0.37
CNR2 P34972 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C19 P33261 1/20 0.37
P2RX7 Q99572 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967713 0.99 CHRM2 (0.43) CHRM2CHRM1KMT2AMEN1ALDH1A1
SCHEMBL14967692 0.99 CHRM2 (0.45) CHRM2CHRM1KMT2AMEN1ALDH1A1
SCHEMBL14967430 0.98 CHRM2 (0.44) CHRM2CHRM1KMT2AMEN1ALDH1A1
SCHEMBL14967269 0.98 CHRM2 (0.42) CHRM2CHRM1KMT2AMEN1ALDH1A1
SCHEMBL14967071 0.97 CHRM1 (0.43) CHRM2CHRM1KMT2AMEN1ALDH1A1
SCHEMBL14968164 0.96 CHRM2 (0.47) CHRM2CHRM1KMT2AMEN1ALDH1A1
SCHEMBL14967445 0.95 CHRM2 (0.46) CHRM2CHRM1KMT2AMEN1ALDH1A1
SCHEMBL14967442 0.94 CHRM1 (0.44) CHRM2CHRM1KMT2AMEN1ALDH1A1
SCHEMBL14967849 0.91 CHRM1 (0.47) CHRM2CHRM1KMT2AMEN1ALDH1A1
SCHEMBL14966959 0.90 CHRM1 (0.47) CHRM2CHRM1KMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed