SCHEMBL14967442

SCHEMBL14967442

CCCCOC(=O)C1(c2ccc(OC)cc2)OC12CCC2

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 2/20 0.44
CHRM2 P08172 1/20 0.44
ALDH1A1 P00352 3/20 0.44
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
LMNA P02545 3/20 0.42
POLB P06746 4/20 0.41
SIGMAR1 Q99720 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MIF P14174 1/20 0.39
CYP2C19 P33261 2/20 0.38
CYP2C9 P11712 1/20 0.38
CHRM5 P08912 1/20 0.37
CHRM3 P20309 1/20 0.37
TSHR P16473 1/20 0.37
CYP3A4 P08684 1/20 0.37
P2RX7 Q99572 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967071 0.98 CHRM1 (0.43) CHRM1CHRM2ALDH1A1KMT2AMEN1
SCHEMBL14968164 0.98 CHRM2 (0.47) CHRM1CHRM2ALDH1A1KMT2AMEN1
SCHEMBL14967269 0.96 CHRM2 (0.42) CHRM1CHRM2ALDH1A1KMT2AMEN1
SCHEMBL14967445 0.96 CHRM2 (0.46) CHRM1CHRM2ALDH1A1KMT2AMEN1
SCHEMBL14967692 0.95 CHRM2 (0.45) CHRM1CHRM2ALDH1A1KMT2AMEN1
SCHEMBL14967430 0.94 CHRM2 (0.44) CHRM1CHRM2ALDH1A1KMT2AMEN1
SCHEMBL14967338 0.94 CHRM2 (0.44) CHRM1CHRM2ALDH1A1KMT2AMEN1
SCHEMBL14967955 0.94 CHRM1 (0.45) CHRM1CHRM2ALDH1A1KMT2AMEN1
SCHEMBL14967713 0.93 CHRM2 (0.43) CHRM1CHRM2ALDH1A1KMT2AMEN1
SCHEMBL14967849 0.91 CHRM1 (0.47) CHRM1CHRM2ALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed