SCHEMBL14967635

SCHEMBL14967635

CCCCCOC(=O)C1OC1(c1ccc(C)cc1)c1ccc(OC)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.38
ALDH1A1 P00352 3/20 0.38
FKBP1A P62942 1/20 0.38
PTGS2 P35354 4/20 0.37
LMNA P02545 2/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
PPARG P37231 3/20 0.36
NPFFR1 Q9GZQ6 1/20 0.36
NPFFR2 Q9Y5X5 1/20 0.36
ELANE P08246 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
MMP2 P08253 1/20 0.36
MMP9 P14780 1/20 0.36
CA9 Q16790 1/20 0.36
GAA P10253 1/20 0.36
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967567 0.99 PPARG (0.38) MIFALDH1A1FKBP1APTGS2LMNA
SCHEMBL16110001 0.98 MIF (0.39) MIFALDH1A1FKBP1ALMNAMAPT
SCHEMBL14967092 0.95 MIF (0.41) MIFALDH1A1PTGS2LMNAPPARG
SCHEMBL14968209 0.94 PPARG (0.41) MIFALDH1A1LMNAPPARGCA1
SCHEMBL14967719 0.93 PPARG (0.40) ALDH1A1LMNAMAPTPPARGTP53
SCHEMBL14968198 0.93 MIF (0.42) MIFALDH1A1LMNAHPGDGAA
SCHEMBL16109764 0.92 HPGD (0.39) ALDH1A1FKBP1ALMNAMAPTHPGD
SCHEMBL14967345 0.92 PPARG (0.42) ALDH1A1LMNAMAPTPPARGTP53
SCHEMBL14966779 0.92 MEN1 (0.40) ALDH1A1LMNAPPARGCYP3A4TSHR
SCHEMBL16109506 0.91 PPARG (0.44) MIFALDH1A1LMNAMAPTPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed