SCHEMBL14968209

SCHEMBL14968209

CCCCCCOC(=O)C1OC1(c1ccc(OC)cc1)c1ccc(OC)cc1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PPARG P37231 3/20 0.41
MMP2 P08253 2/20 0.40
MMP9 P14780 2/20 0.40
MIF P14174 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
ALDH1A1 P00352 2/20 0.40
TSHR P16473 2/20 0.40
LMNA P02545 1/20 0.40
TP53 P04637 1/20 0.39
STS P08842 4/20 0.38
MMP8 P22894 1/20 0.38
MMP13 P45452 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967092 0.99 MIF (0.41) PPARGMMP2MMP9MIFCA1
SCHEMBL14968198 0.96 MIF (0.42) MIFALDH1A1TSHRLMNA
SCHEMBL16109672 0.95 PPARG (0.46) PPARGALDH1A1TSHRLMNATP53
SCHEMBL14967567 0.95 PPARG (0.38) PPARGMMP2MMP9MIFCA1
SCHEMBL14967635 0.94 MIF (0.38) PPARGMMP2MMP9MIFCA1
SCHEMBL16109506 0.94 PPARG (0.44) PPARGMIFALDH1A1TSHRLMNA
SCHEMBL16110001 0.91 MIF (0.39) MIFALDH1A1TSHRLMNA
SCHEMBL16109798 0.91 L3MBTL1 (0.40) PPARGMIFALDH1A1TSHRLMNA
SCHEMBL14967456 0.90 MAPKAPK2 (0.39) MIFALDH1A1TSHRLMNA
SCHEMBL14967345 0.87 PPARG (0.42) PPARGALDH1A1TSHRLMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed