SCHEMBL14967680

SCHEMBL14967680

CCC1(C(=O)OC)OC1c1ccc(OC)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
GAA P10253 4/20 0.42
HSD17B10 Q99714 2/20 0.42
KDM4E B2RXH2 1/20 0.42
LMNA P02545 1/20 0.42
HPGD P15428 1/20 0.42
OPRK1 P41145 1/20 0.40
MEN1 O00255 1/20 0.39
TSHR P16473 1/20 0.39
KMT2A Q03164 1/20 0.39
CA1 P00915 3/20 0.38
CA2 P00918 3/20 0.38
MTNR1A P48039 1/20 0.38
MTNR1B P49286 1/20 0.38
HTT P42858 2/20 0.37
NPC1 O15118 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
POLB P06746 1/20 0.37
RAB9A P51151 1/20 0.37
GSK3B P49841 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14968170 0.89 ALDH1A1 (0.49) ALDH1A1GAAHSD17B10KDM4ELMNA
SCHEMBL16108809 0.88 KMT2A (0.41) ALDH1A1GAAHSD17B10KDM4ELMNA
SCHEMBL14968220 0.87 CYP3A4 (0.36) ALDH1A1GAAHSD17B10LMNAHPGD
SCHEMBL9355324 0.87 ALDH1A1 (0.43) ALDH1A1GAAHSD17B10KDM4ELMNA
SCHEMBL9355549 0.87 ALDH1A1 (0.43) ALDH1A1GAAHSD17B10KDM4ELMNA
SCHEMBL16109030 0.86 NPC1 (0.40) ALDH1A1GAAHSD17B10KDM4ELMNA
SCHEMBL14967171 0.86 ALDH1A1 (0.41) ALDH1A1GAAHSD17B10KDM4ELMNA
SCHEMBL14967029 0.86 ALDH1A1 (0.39) ALDH1A1GAAHSD17B10KDM4ELMNA
SCHEMBL16109787 0.86 SLC6A4 (0.38) ALDH1A1GAAHSD17B10KDM4ELMNA
SCHEMBL16108675 0.86 SLC6A4 (0.40) ALDH1A1GAAHSD17B10KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed