SCHEMBL14968239

SCHEMBL14968239

Cc1ccc(C2OC2(C(=O)OC2CC2)c2ccc(C)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN1A P35498 1/20 0.37
SCN2A Q99250 1/20 0.37
SCN3A Q9NY46 1/20 0.37
OPRM1 P35372 1/20 0.34
SLC6A2 P23975 2/20 0.34
SLC6A4 P31645 2/20 0.34
SLC6A3 Q01959 2/20 0.34
CHRNA1 P02708 1/20 0.34
CHRNG P07510 1/20 0.34
ITGA5 P08648 1/20 0.34
CHRNB1 P11230 1/20 0.34
CHRNB2 P17787 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA4 P43681 1/20 0.34
CHRND Q07001 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 2/20 0.33
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967716 0.95 ALDH1A1 (0.39) SCN1ASCN2ASCN3ASLC6A2SLC6A4
SCHEMBL14968154 0.95 CHRNA1 (0.40) SCN1ASCN2ASCN3ASLC6A2SLC6A4
SCHEMBL14967614 0.93 ALDH1A1 (0.40) SCN1ASCN2ASCN3ASLC6A2SLC6A4
SCHEMBL16108954 0.93 CHRM3 (0.40) SCN1ASCN2ASCN3ASLC6A2SLC6A4
SCHEMBL16109833 0.93 MEN1 (0.43) SLC6A2SLC6A4SLC6A3MEN1KMT2A
SCHEMBL14967036 0.89 CHRM3 (0.41) SCN1ASCN2ASCN3ASLC6A2SLC6A4
SCHEMBL14967761 0.89 CHRM3 (0.41) SCN1ASCN2ASCN3ASLC6A2SLC6A4
SCHEMBL16108684 0.88 KMT2A (0.40) SLC6A4SLC6A3MEN1KMT2AALDH1A1
SCHEMBL16109939 0.88 KMT2A (0.40) SLC6A2SLC6A4SLC6A3CHRNA1CHRNG
SCHEMBL16109679 0.87 CHRM3 (0.43) SLC6A2SLC6A4SLC6A3CHRNA1CHRNG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed