Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 9/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 9/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14979776 | 0.87 | CYP3A4 (0.46) | — | |
| SCHEMBL6126547 | 0.87 | CYP3A4 (0.38) | HCRTR1HCRTR2 | |
| SCHEMBL15052198 | 0.87 | HCRTR1 (0.35) | PARP1HCRTR1HCRTR2 | |
| SCHEMBL21330022 | 0.87 | CYP3A4 (0.38) | HCRTR1HCRTR2 | |
| SCHEMBL6126614 | 0.87 | HCRTR1 (0.39) | HCRTR1HCRTR2 | |
| SCHEMBL19528097 | 0.85 | CYP3A4 (0.44) | — | |
| SCHEMBL14979634 | 0.85 | PTGES (0.37) | PARP1HCRTR1HCRTR2 | |
| SCHEMBL8752362 | 0.79 | CYP3A4 (0.44) | — | |
| SCHEMBL14979730 | 0.78 | CYP3A4 (0.45) | — | |
| SCHEMBL22364713 | 0.77 | CYP3A4 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2635588-A1 | CONDENSED IMIDAZOLYLIMIDAZOLES AS ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2013-09-11 | — | — | EP | disclosed |
| WO-2013075029-A1 | CONDENSED IMIDAZOLYLIMIDAZOLES AS ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2013-05-23 | — | — | WO | disclosed |