Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.79 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.67 |
| ▸ | RARB | P10826 | 3/20 | 0.63 |
| ▸ | PPARG | P37231 | 3/20 | 0.63 |
| ▸ | PPARA | Q07869 | 1/20 | 0.63 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.60 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12112441 | 1.00 | PLK1 (0.79) | PLK1TP53TSHRPLA2G4BRARB | |
| SCHEMBL12113898 | 1.00 | PLK1 (0.79) | PLK1TP53TSHRPLA2G4BRARB | |
| SCHEMBL14969336 | 0.98 | PLK1 (0.81) | PLK1TP53TSHRPLA2G4BRARB | |
| SCHEMBL12839873 | 0.95 | PLK1 (0.87) | PLK1TP53TSHRPLA2G4B | |
| SCHEMBL23484979 | 0.94 | PLK1 (0.74) | PLK1TP53TSHRPLA2G4BRARB | |
| SCHEMBL11609121 | 0.89 | TP53 (0.71) | PLK1TP53TSHRPLA2G4BRARB | |
| SCHEMBL11962158 | 0.88 | PLK1 (1.00) | PLK1TSHR | |
| SCHEMBL3952381 | 0.87 | TP53 (0.69) | TP53TSHRPLA2G4BRARBPPARG | |
| SCHEMBL28467816 | 0.87 | TP53 (0.69) | TP53TSHRPLA2G4BRARBPPARG | |
| SCHEMBL4822746 | 0.87 | TP53 (0.69) | TP53TSHRPLA2G4BRARBPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130131134-A1 | PHENYLPROPIONIC ACID DERIVATIVE AND USE THEREOF | MORITA KOHEI (JP) | 2013-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131134-A1 | PHENYLPROPIONIC ACID DERIVATIVE AND USE THEREOF | PLA2G12A, PLA2G4A, PLA2G4B | PLK1 1861/4885TP53 4654/4885TSHR 4126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.