Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | XBP1 | P17861 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3198298 | 1.00 | MAPT (0.63) | MAPTALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL3198294 | 1.00 | MAPT (0.63) | MAPTALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL8338435 | 0.90 | ALDH1A1 (0.54) | MAPTALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL13377968 | 0.89 | SMN1; SMN2 (0.68) | MAPTALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL13377971 | 0.85 | MAPT (0.55) | MAPTALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL8342632 | 0.84 | MAPT (0.57) | MAPTALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL3196296 | 0.84 | ALDH1A1 (0.50) | MAPTALDH1A1LMNAGAAMEN1 | |
| SCHEMBL3196309 | 0.84 | ALDH1A1 (0.50) | MAPTALDH1A1LMNAGAAMEN1 | |
| SCHEMBL13377982 | 0.83 | MAPT (0.67) | MAPTALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL2879006 | 0.83 | MAPT (0.67) | MAPTALDH1A1LMNAGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594843-B1 | METHOD FOR PRODUCING AN OPTICALLY ACTIVE beta-amino acid derivative | TAKASAGO PERFUMERY CO LTD (JP) | 2013-05-22 | — | — | EP | disclosed |